Validation of a novel microradiography device for characterization of bone ineralization

Florian Montagner (1) , Valérie Kaftandjian (2) , Delphine Farlay (1) , Daniel Brau (3) , Georges Boivin (1) , Hélène Follet (1)

1 LYOS - Physiopathologie, diagnostic et traitements des maladies osseuses / Pathophysiology, Diagnosis & Treatments of Bone Diseases
2 LVA - Laboratoire Vibrations Acoustique
3 Photonic Science

In order to simplify bone mineralization measurements, a system using radiographic films has been updated with a 13 digital detector. The objective of this paper was to validate this new device. Technologies and physical phenomena involved 14 in both systems (radiographic films and digital detector) are different. The methodology used to compare the two systems was 15 based on image quality and assessed on two main parameters: contrast to noise ratio and spatial resolution. Results showed 16 that the contrast to noise ratio was similar between the two systems, provided that acquisition parameters were optimized. With 17 regard to spatial resolution, a magnification factor of at least 4 or more was required to achieve the same resolution as films. 18 A final validation was also shown on a real image of a bone sample. The results showed that both systems have similar image 19 quality performances, and the system using digital detector has several advantages (easier to use than films, no consumables 20 and faster acquisition time).

Mots clés: quantitative microradiography; Mineralization of bone; digital detector; spatial resolution; contrast to noise ratio

Domaines: Sciences de l'ingénieur [physics]

Florian Montagner, Valérie Kaftandjian, Delphine Farlay, Daniel Brau, Georges Boivin, et al.. Validation of a novel microradiography device for characterization of bone ineralization. Journal of X-Ray Science and Technology, 2015, 23 (2), pp.201-211. ⟨10.3233/XST-150481⟩. ⟨hal-01282074⟩