Development of a novel sensitive molecularly imprinted polymer sensor based on electropolymerization of a microporous-metal-organic framework for tetracycline detection in honey

Abstract : Electrochemical sensor for the detection of tetracycline, based on a gold electrode surface modified with a molecularly imprinted polymer microporous-metal-organic framework, is described. Imprinted gold nanoparticles composites are assembled on Au surfaces by the electropolymerization of p-aminothiophenol functionalized gold nanoparticles in the presence of the imprint molecule. The electrochemical sensor was characterized by linear sweep voltammetry in the presence of hexacyanoferrate/hexacyanoferrite as redox probe. In order to achieve optimal preconcentration, the influence of various parameters such as extraction and incubation times, washing and eluting solutions was evaluated. The sensor showed a linear range from 224 fM to 22.4 nM and a limit of detection of 0.22 fM. The proposed method was successfully applied to determine tetracycline in honey. The recoveries of tetracycline are in the range of 101.8 %−106.0 % with an RSD ≤8.3%.
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Submitted on : Wednesday, February 17, 2016 - 12:03:55 PM
Last modification on : Thursday, July 26, 2018 - 1:10:21 AM

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Madiha Bougrini, Anca Florea, Cecilia Cristea, Robert Sandulescu, Francis Vocanson, et al.. Development of a novel sensitive molecularly imprinted polymer sensor based on electropolymerization of a microporous-metal-organic framework for tetracycline detection in honey. Food Control, Elsevier, 2016, 59, pp.424-429. ⟨10.1016/j.foodcont.2015.06.002⟩. ⟨hal-01275314⟩

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