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Article Dans Une Revue Current Topics in Medicinal Chemistry Année : 2015

Sol-gel Encapsulation of Biomolecules and Cells for Medicinal Applications

Xiaolin Wang
Nada Ben Ahmed
  • Fonction : Auteur
Gisela S. Alvarez
  • Fonction : Auteur
Maria V. Tuttolomondo
  • Fonction : Auteur
Christophe Hélary
Thibaud Coradin

Résumé

The sol-gel process provides a robust and versatile technology for the immobilization of biologicals. A wide range of inorganic, composites and hybrid materials can be prepared to encapsulate molecular drugs, proteins, antibodies/antigens, enzymes, nucleic acids, prokaryotic and eukaryotic cells into bulk gels, particles and films. This review describes the applications of sol-gel encapsulation relevant to medicinal chemistry focusing on the recent development of biosensors as well as systems for production, screening and delivery of bioactive compounds and biomaterials.
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Dates et versions

hal-01274323 , version 1 (15-02-2016)

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Citer

Xiaolin Wang, Nada Ben Ahmed, Gisela S. Alvarez, Maria V. Tuttolomondo, Christophe Hélary, et al.. Sol-gel Encapsulation of Biomolecules and Cells for Medicinal Applications. Current Topics in Medicinal Chemistry, 2015, 15 (3), pp.223-244. ⟨10.2174/1568026614666141229112734⟩. ⟨hal-01274323⟩
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