Identification and Characterization of Botulinum Neurotoxin A Substrate Binding Pockets and Their Re-Engineering for Human SNAP-23

Stefan Sikorra (1) , Christa Litschko (1) , Carina Müller (1) , Nadine Thiel (1) , Thierry Galli (2, 3, 4) , Timo Eichner (5) , Thomas Binz (1)

1 Institut für Physiologische Chemie, OE 4310
2 USPC - Université Sorbonne Paris Cité
3 IJM (UMR_7592) - Institut Jacques Monod
4 Trafic Membranaire et Morphogenèse Neuronale & Epithéliale
5 Department of Biochemistry

Domaines: Biochimie, Biologie Moléculaire

Stefan Sikorra, Christa Litschko, Carina Müller, Nadine Thiel, Thierry Galli, et al.. Identification and Characterization of Botulinum Neurotoxin A Substrate Binding Pockets and Their Re-Engineering for Human SNAP-23. Molecular biology today : the online journal of molecular biology, 2016, 428 (2), ⟨10.1016/j.jmb.2015.10.024⟩. ⟨hal-01269586⟩