Water-Soluble Gold–N-Heterocyclic Carbene Complexes for the Catalytic Homogeneous Acid- and Silver-Free Hydration of Hydrophilic Alkynes.

Houssein Ibrahim (1, 2) , Pierre De frémont (2) , Pierre Braunstein (2) , Vincent Théry (1) , Lionel Nauton (1) , Federico Cisnetti (1) , Arnaud Gautier (1)

1 ICCF - Institut de Chimie de Clermont-Ferrand
2 Institut de Chimie de Strasbourg

Water-soluble gold(III/I) N-heterocylic carbene complexes behave as efficient catalysts for the hydration of terminal alkynes in neat water. The transformation proceeds in the absence of Brønsted acids or halide scavengers and is suitable for sensitive substrates. Kinetic profiles and DFT studies provide a clear picture of intermediates present during catalysis.

Mots clés: alkynes; gold; N-heterocyclic carbenes (NHCs); water-soluble catalysts

Domaines: Chimie

Houssein Ibrahim, Pierre De frémont, Pierre Braunstein, Vincent Théry, Lionel Nauton, et al.. Water-Soluble Gold–N-Heterocyclic Carbene Complexes for the Catalytic Homogeneous Acid- and Silver-Free Hydration of Hydrophilic Alkynes.. Advanced Synthesis and Catalysis, 2015, 357, pp.3893-3900. ⟨10.1002/adsc.201500729⟩. ⟨hal-01264762⟩