Skip to Main content Skip to Navigation
New interface
Journal articles

Antiviral immunity in marine molluscs

Abstract : Marine molluscs, like all living organisms, are constantly exposed to viruses and have evolved efficient antiviral defences. We review here recent developments in molluscan antiviral immunity against viruses belonging to the order Herpesvirales. Emerging results suggest an interferon-like response and autophagy are involved in the antiviral defence of bivalves to viral infection. Multi-functional plasma proteins from gastropods and bivalves have been identified to have broad-spectrum antiviral activity against mammalian viruses. The antiviral defences present in molluscs can be enhanced by genetic selection, as shown by the presence of oyster strains specifically resistant to ostreid herpesvirus type 1. Whether varying amounts or different isoforms of these antiviral plasma proteins contributes to genetic resistance is worthy of further research. Other evolutionarily conserved antiviral mechanisms, such as RNA interference and apoptosis, still need further characterization
Document type :
Journal articles
Complete list of metadata
Contributor : Anne Modat Connect in order to contact the contributor
Submitted on : Tuesday, January 12, 2021 - 11:53:01 AM
Last modification on : Thursday, December 1, 2022 - 6:26:12 AM
Long-term archiving on: : Tuesday, April 13, 2021 - 6:26:10 PM


Publisher files allowed on an open archive




Timothy Green, David Raftos, Peter Speck,, Caroline Montagnani. Antiviral immunity in marine molluscs. Journal of General Virology, 2015, 96, 96, pp.2471-2482. ⟨10.1099/jgv.0.000244⟩. ⟨hal-01259807⟩



Record views


Files downloads