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Conference papers
Completing signaling networks by abductive reasoning with perturbation experiments
Adrien Rougny
1
Yoshitaka Yamamoto
2
Hidetomo Nabeshima
2
Gauvain Bourgne
3
Anne Poupon
4
Katsumi Inoue
5
Christine Froidevaux
1
Adrien Rougny 1
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Author
Yoshitaka Yamamoto 2
Author
Hidetomo Nabeshima 2
Author
Gauvain Bourgne 3
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Author IdHAL : gauvain-bourgne
Anne Poupon 4
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Author
Katsumi Inoue 5
Mail : Site :
Author
Christine Froidevaux 1
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Author IdHAL : christine-froidevaux
1
LRI - Laboratoire de Recherche en Informatique (LRI - Bâtiments 650-660 Université Paris-Sud 91405 Orsay Cedex - France)
- CNRS - Centre National de la Recherche Scientifique : UMR8623 (France)
- UP11 - Université Paris-Sud - Paris 11 (Bâtiment 300 - 91405 Orsay cedex - France)
- CentraleSupélec (3, rue Joliot Curie, Plateau de Moulon, 91192 GIF-SUR-YVETTE Cedex - France)
2
Yamanashi University (Kofu Campus 4-4-37, Takeda, Kofu, Yamanashi, 400-8510 Japan - Japan)
3
ACASA - Agents Cognitifs et Apprentissage Symbolique Automatique (France)
- LIP6 - Laboratoire d'Informatique de Paris 6 (4 Place JUSSIEU 75252 PARIS CEDEX 05 - France)
- CNRS - Centre National de la Recherche Scientifique : UMR7606 (France)
- UPMC - Université Pierre et Marie Curie - Paris 6 (4 place Jussieu - 75005 Paris - France)
4
PRC - Physiologie de la reproduction et des comportements [Nouzilly] (Centre de Recherches de Tours 37380 Nouzilly - France)
- CNRS - Centre National de la Recherche Scientifique : UMR7247 (France)
- Université de Tours (60 rue du Plat d'Étain, 37020 Tours cedex 1 - France)
- Institut Français du Cheval et de l'Equitation [Saumur] (Terrefort, BP 207, F-49411 Saumur - France)
- INRA - Institut National de la Recherche Agronomique : UR0085 (France)
5
NII - National Institute of Informatics (2-1-2 Hitotsubashi, Chiyoda-ku, Tokyo 101-8430 - Japan)
Abstract : We propose in this paper an abductive method that allows, given a biological network, to check whether some experimental observations can be causally explained by the network and to use the unexplained observations to complete the network. We then apply the method on the FSHR-induced signaling network.
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Complete list of metadatas
https://hal.archives-ouvertes.fr/hal-01259205
Contributor : Adrien Rougny <>
Submitted on : Wednesday, January 20, 2016 - 10:23:42 AM
Last modification on : Tuesday, April 21, 2020 - 1:10:23 AM
Contributor : Adrien Rougny <>
Submitted on : Wednesday, January 20, 2016 - 10:23:42 AM
Last modification on : Tuesday, April 21, 2020 - 1:10:23 AM
Identifiers
- HAL Id : hal-01259205, version 1
Collections
CNRS | INRA | UPMC | UMR8623 | LIP6 | LRI-BIOINFO | UNIV-PARIS-SACLAY | CENTRALESUPELEC | UNIV-TOURS | SORBONNE-UNIVERSITE | SU-SCIENCES | INRAE
Citation
Adrien Rougny, Yoshitaka Yamamoto, Hidetomo Nabeshima, Gauvain Bourgne, Anne Poupon, et al.. Completing signaling networks by abductive reasoning with perturbation experiments. 25th International Conference on Inductive Logic Programming, Aug 2015, Kyoto, Japan. ⟨hal-01259205⟩
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