A crucial requirement for Hedgehog signaling in small cell lung cancer, Nature Medicine, vol.128, issue.11, pp.1504-1512, 2011. ,
DOI : 10.1101/gad.1902910
Frequent requirement of hedgehog signaling in non-small cell lung carcinoma, Oncogene, vol.207, issue.7, pp.1046-55, 2007. ,
DOI : 10.1038/sj.onc.1209860
Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas, Lung Cancer, vol.66, issue.1, pp.64-74, 2009. ,
DOI : 10.1016/j.lungcan.2009.01.007
Hedgehog signaling pathway molecules and ALDH1A1 expression in early-stage non-small cell lung cancer, Lung Cancer, vol.76, issue.2, pp.191-197, 2012. ,
DOI : 10.1016/j.lungcan.2011.10.015
International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma, Journal of Thoracic Oncology, vol.6, issue.2, pp.244-85, 2011. ,
DOI : 10.1097/JTO.0b013e318206a221
URL : https://hal.archives-ouvertes.fr/inserm-00561753
Expression of hedgehog signaling molecules as a prognostic indicator of oral squamous cell carcinoma, Head & Neck, vol.8, issue.11, pp.1556-61, 2012. ,
DOI : 10.1002/hed.21958
Combination of morphological feature analysis and immunohistochemistry is useful for screening of EML4-ALK-positive lung adenocarcinoma, Journal of Clinical Pathology, vol.63, issue.12, pp.1066-70, 2010. ,
DOI : 10.1136/jcp.2010.081166
Correlation of IHC and FISH for ALK Gene Rearrangement in Non-small Cell Lung Carcinoma: IHC Score Algorithm for FISH, Journal of Thoracic Oncology, vol.6, issue.3, pp.459-65, 2011. ,
DOI : 10.1097/JTO.0b013e318209edb9
Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method, Cancer Research, vol.70, issue.2, pp.440-446, 2010. ,
DOI : 10.1158/0008-5472.CAN-09-1947
Hedgehog-GLI Signaling Inhibition Suppresses Tumor Growth in Squamous Lung Cancer, Clinical Cancer Research, vol.20, issue.6, pp.1566-75, 2014. ,
DOI : 10.1158/1078-0432.CCR-13-2195
Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport, Oncogene, vol.7, issue.38, pp.5674-5683, 2007. ,
DOI : 10.1038/sj.onc.1210356
The hedgehog pathway inhibitor GDC-0449 alters intracellular Ca2+ homeostasis and inhibits cell growth in cisplatin-resistant lung cancer cells, Anticancer Res, vol.32, pp.89-94, 2012. ,
Inhibition of Hedgehog signaling sensitizes NSCLC cells to standard therapies through modulation of EMT-regulating miRNAs, Journal of Hematology & Oncology, vol.6, issue.1, p.77, 2013. ,
DOI : 10.1158/1541-7786.MCR-10-0497
Hedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas, Journal of Experimental & Clinical Cancer Research, vol.33, issue.1, p.34, 2014. ,
DOI : 10.1016/j.ctrv.2010.11.004
Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site, Gene, vol.330, pp.101-115, 2004. ,
DOI : 10.1016/j.gene.2004.01.010
Gli2 is expressed in normal human epidermidis and BCC and induces Gli1 expression by binding to its promoter ,
Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling, Experimental Cell Research, vol.312, issue.11 ,
DOI : 10.1016/j.yexcr.2006.02.019
Effects of the Hedgehog pathway inhibitor GDC-0449 on lung cancer cell lines are mediated by side populations, Clinical and Experimental Medicine, vol.31, issue.1, pp.25-30, 2012. ,
DOI : 10.1007/s10238-011-0135-8
Gli as a Novel Therapeutic Target in Malignant Pleural Mesothelioma, PLoS ONE, vol.18, issue.3, p.57346, 2013. ,
DOI : 10.1371/journal.pone.0057346.s001
Three-arm randomized phase II study of cisplatin and etoposide (CE) versus CE with either vismodegib (V) or cixutumumab (Cx) for patients with extensive stage-small cell lung cancer (ES- SCLC) (ECOG 1508), J Clin Oncol, 2013. ,