A. L. Demain, Importance of microbial natural products and the need to revitalize their discovery, Journal of Industrial Microbiology & Biotechnology, vol.21, issue.4, pp.185-201, 2014.
DOI : 10.1007/s10295-013-1325-z

P. A. Jose, S. Robinson, and D. Jebakumar, Non-streptomycete actinomycetes nourish the current microbial antibiotic drug discovery, Frontiers in Microbiology, vol.4, 2008.
DOI : 10.3389/fmicb.2013.00240

F. E. Koehn and G. Carter, The evolving role of natural products in drug discovery, Nature Reviews Drug Discovery, vol.8, issue.3, pp.206-226, 2005.
DOI : 10.1038/nrd1657

J. Bérdy, Bioactive Microbial Metabolites, The Journal of Antibiotics, vol.21, issue.1, pp.1-26, 2005.
DOI : 10.1038/ja.2005.1

A. T. Bull, J. E. Stach, A. C. Ward, and M. Goodfellow, Marine actinobacteria: perspectives, challenges, future directions, Antonie van Leeuwenhoek, vol.21, issue.1, pp.65-79, 2005.
DOI : 10.1007/s10482-004-6562-8

H. Fiedler, Marine actinomycetes as a source of novel secondary metabolites, Antonie van Leeuwenhoek, vol.69, issue.1, pp.37-42, 2005.
DOI : 10.1007/s10482-004-6538-8

P. Fu, M. Johnson, H. Chen, B. A. Posner, &. J. Macmillan et al., sp., Journal of Natural Products, vol.77, issue.5, pp.1245-1248, 2014.
DOI : 10.1021/np500207p

M. Goodfellow, Verrucosispora maris sp. nov., a novel deep-sea actinomycete isolated from a marine sediment which produces abyssomicins, Antonie van Leeuwenhoek, vol.100, issue.1, pp.185-93, 2012.
DOI : 10.1007/s10482-011-9651-5

D. Oh, P. G. Williams, C. Kauffman, P. R. Jensen, and W. Fenical, ???, Organic Letters, vol.8, issue.6, pp.1021-1025, 2006.
DOI : 10.1021/ol052686b

E. T. Watson and S. Williams, Studies on the ecology of actinomycetes in soil??? VII. Actinomycetes in a coastal sand belt, Soil Biology and Biochemistry, vol.6, issue.1, pp.43-52, 1974.
DOI : 10.1016/0038-0717(74)90010-8

S. Antony-babu, J. E. Stach, and M. Goodfellow, Genetic and phenotypic evidence for Streptomyces griseus ecovars isolated from a beach and dune sand system, Antonie van Leeuwenhoek, vol.19, issue.1, pp.63-74, 2008.
DOI : 10.1007/s10482-008-9246-y

K. Hong, Actinomycetes for Marine Drug Discovery Isolated from Mangrove Soils and Plants in China, Marine Drugs, vol.7, issue.1, pp.24-44, 2009.
DOI : 10.3390/md7010024

M. Lauterwein, M. Oethinger, K. Belsner, T. Peters, and R. Marre, In vitro activities of the lichen secondary metabolites vulpinic acid, (+)-usnic acid, and (-)-usnic acid against aerobic and anaerobic microorganisms, Usnic Acid , and (?)-Usnic Acid against Aerobic and Anaerobic Microorganisms, pp.2541-2543, 1995.
DOI : 10.1128/AAC.39.11.2541

K. Ingolfsdottir, Usnic acid, Phytochemistry, vol.61, issue.7, pp.729-736, 2002.
DOI : 10.1016/S0031-9422(02)00383-7

K. Molnár and E. Farkas, Current Results on Biological Activities of Lichen Secondary Metabolites: a Review, Zeitschrift f??r Naturforschung C, vol.65, issue.3-4, pp.157-73, 2010.
DOI : 10.1515/znc-2010-3-401

V. Shukla, G. P. Joshi, and M. S. Rawat, Lichens as a potential natural source of bioactive compounds: a review, Phytochemistry Reviews, vol.2, issue.6, pp.303-314, 2010.
DOI : 10.1007/s11101-010-9189-6

G. Shrestha, . St, and L. L. Clair, Lichens: a promising source of antibiotic and anticancer drugs, Phytochemistry Reviews, vol.22, issue.1, pp.229-244, 2013.
DOI : 10.1007/s11101-013-9283-7

S. T. Bates, G. W. Cropsey, J. G. Caporaso, R. Knight, and . Fierer, 15839 | DOi: 10.1038/srep15839 18

M. Cardinale, G. Berg, M. Grube, J. Vieira-de-castro, and H. Müller, In situ analysis of the bacterial community associated with the reindeer lichen Cladonia arbuscula reveals predominance of Alphaproteobacteria, FEMS Microbiology Ecology, vol.66, issue.1, pp.63-71, 2008.
DOI : 10.1111/j.1574-6941.2008.00546.x

M. Cardinale, A. M. Puglia, and M. Grube, Molecular analysis of lichen-associated bacterial communities, FEMS Microbiology Ecology, vol.57, issue.3, pp.484-495, 2006.
DOI : 10.1111/j.1574-6941.2006.00133.x

I. González, A. Ayuso-sacido, A. Anderson, and O. Genilloud, Actinomycetes isolated from lichens: Evaluation of their diversity and detection of biosynthetic gene sequences, FEMS Microbiology Ecology, vol.54, issue.3, pp.401-416, 2005.
DOI : 10.1016/j.femsec.2005.05.004

M. Grube and G. Berg, Microbial consortia of bacteria and fungi with focus on the lichen symbiosis, Fungal Biology Reviews, vol.23, issue.3, pp.72-85, 2009.
DOI : 10.1016/j.fbr.2009.10.001

M. Grube, M. Cardinale, J. De-castro, H. Mu, and G. Berg, Species-specific structural and functional diversity of bacterial communities in lichen symbioses, The ISME Journal, vol.64, issue.9, pp.1105-1115, 2009.
DOI : 10.1126/science.1111347

B. P. Hodkinson and F. Lutzoni, A microbiotic survey of lichen-associated bacteria reveals a new lineage from the Rhizobiales, Symbiosis, vol.6, issue.3, pp.163-180, 2010.
DOI : 10.1007/s13199-009-0049-3

C. M. Liba, Nitrogen-fixing chemo-organotrophic bacteria isolated from cyanobacteria-deprived lichens and their ability to solubilize phosphate and to release amino acids and phytohormones, Journal of Applied Microbiology, vol.46, issue.5, pp.1076-86, 2006.
DOI : 10.1007/BF02226804

L. Muggia, B. Klug, G. Berg, and M. Grube, Localization of bacteria in lichens from Alpine soil crusts by fluorescence in situ hybridization, Applied Soil Ecology, vol.68, pp.20-25, 2013.
DOI : 10.1016/j.apsoil.2013.03.008

M. Cardinale, M. Grube, J. V. Castro, H. Müller, and G. Berg, Bacterial taxa associated with the lung lichen Lobaria pulmonaria are differentially shaped by geography and habitat, FEMS Microbiology Letters, vol.329, issue.2, pp.111-116, 2012.
DOI : 10.1111/j.1574-6968.2012.02508.x

T. Bjelland, Microbial metacommunities in the lichen-rock habitat, Environmental Microbiology Reports, vol.73, issue.4, pp.434-442, 2011.
DOI : 10.1111/j.1758-2229.2010.00206.x

M. A. Sigurbjörnsdóttir, S. Heiðmarsson, A. R. Jónsdóttir, and O. Vilhelmsson, Novel bacteria associated with Arctic seashore lichens have potential roles in nutrient scavenging, Canadian Journal of Microbiology, vol.60, issue.5, pp.307-317, 2014.
DOI : 10.1139/cjm-2013-0888

O. Kim, Introducing EzTaxon-e: a prokaryotic 16S rRNA gene sequence database with phylotypes that represent uncultured species, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol.62, issue.Pt 3, pp.716-721, 2012.
DOI : 10.1099/ijs.0.038075-0

Y. E. Navarro-noya, Pyrosequencing Analysis of the Bacterial Community in Drinking Water Wells, Microbial Ecology, vol.61, issue.1, pp.19-29, 2013.
DOI : 10.1007/s00248-013-0222-3

L. Maldonado, Diversity of cultivable actinobacteria in geographically widespread marine sediments, Antonie van Leeuwenhoek, vol.99, issue.8, pp.11-19, 2005.
DOI : 10.1007/s10482-004-6525-0

W. Fenical and P. Jensen, Developing a new resource for drug discovery: marine actinomycete bacteria, Nature Chemical Biology, vol.3, issue.12, pp.666-73, 2006.
DOI : 10.1016/S0378-1097(00)00184-1

H. Bredholdt, Rare actinomycete bacteria from the shallow water sediments of the Trondheim fjord, Norway: isolation, diversity and biological activity, Environmental Microbiology, vol.5, issue.11, pp.2756-64, 2007.
DOI : 10.1099/ijs.0.03036-0

M. E. Trujillo, The genus Micromonospora is widespread in legume root nodules: the example of Lupinus angustifolius, The ISME Journal, vol.5, issue.10, pp.1265-81, 2010.
DOI : 10.1128/AEM.70.11.6619-6627.2004

D. I. Kurtböke, Biodiscovery from rare actinomycetes: an eco-taxonomical perspective, Applied Microbiology and Biotechnology, vol.105, issue.22, pp.1843-52, 2012.
DOI : 10.1007/s00253-012-3898-2

W. Ai, Axinelline A, a new COX-2 inhibitor from Streptomyces axinellae SCSIO02208, Nat. Prod. Res, pp.1-6, 2014.

M. H. Farris and A. D. Steinberg, Mitrecin A, an endolysin-like bacteriolytic enzyme from a newly isolated soil streptomycete, Letters in Applied Microbiology, vol.171, issue.5, pp.493-502, 2014.
DOI : 10.1111/lam.12220

E. Harunari, Hyaluromycin, a New Hyaluronidase Inhibitor of Polyketide Origin from Marine Streptomyces sp., Marine Drugs, vol.12, issue.1, pp.491-507, 2014.
DOI : 10.3390/md12010491

X. He, Pelopuradazole, a new imidazole derivative alkaloid from the marine bacteria Pelomonas puraquae sp. nov, Nat. Prod. Res, vol.13, 2014.

K. H. Kim, Natalamycin A, an ansamycin from a termite-associated Streptomyces sp., Chem. Sci., vol.9, issue.11, pp.10-1039, 2014.
DOI : 10.1039/C4SC01136H

J. Lee, Anmindenols A and B, Inducible Nitric Oxide Synthase Inhibitors from a Marine-Derived Streptomyces sp, J. Nat. Prod, 2014.

H. B. Park, J. K. Lee, K. R. Lee, and H. C. Kwon, Angumycinones A and B, two new angucyclic quinones from Streptomyces sp. KMC004 isolated from acidic mine drainage, Tetrahedron Letters, vol.55, issue.1, pp.63-66, 2014.
DOI : 10.1016/j.tetlet.2013.10.112

R. Raju, Oleamycins A and B: new antibacterial cyclic hexadepsipeptides isolated from a terrestrial Streptomyces sp., The Journal of Antibiotics, vol.67, issue.4, 2014.
DOI : 10.1038/nchembio.159

R. Raju, sp. (CMB-M0244), Organic Letters, vol.16, issue.6, pp.1716-1725, 2014.
DOI : 10.1021/ol5003913

A. Vartak, Isolation of a new broad spectrum antifungal polyene from Streptomyces sp. MTCC 5680, Lett. Appl. Microbiol, 2014.

D. Xu, W. Ye, Y. Han, Z. Deng, and K. Hong, Natural Products from Mangrove Actinomycetes, Marine Drugs, vol.12, issue.5, pp.2590-2613, 2014.
DOI : 10.3390/md12052590

URL : http://doi.org/10.3390/md12052590

J. Zhang, Ansamycin Macrodilactams from Streptomyces sp, Org. Lett, 2014.
DOI : 10.1021/ol501072t

M. Takagi and K. Shin-ya, New species of actinomycetes do not always produce new compounds with high frequency, The Journal of Antibiotics, vol.64, issue.10, pp.699-701, 2011.
DOI : 10.1021/np200054s

C. Hertweck, The Biosynthetic Logic of Polyketide Diversity, Angewandte Chemie International Edition, vol.45, issue.26, pp.4688-716, 2009.
DOI : 10.1002/anie.200806121

J. Davies, Uncialamycin, A New Enediyne Antibiotic, Organic Letters, vol.7, issue.23, pp.5233-5236, 2005.
DOI : 10.1021/ol052081f

K. Motohashi, M. Takagi, H. Yamamura, M. Hayakawa, and K. Shin-ya, A new angucycline and a new butenolide isolated from lichen-derived Streptomyces spp., The Journal of Antibiotics, vol.92, issue.9, pp.545-548, 2010.
DOI : 10.1111/j.1574-6968.1995.tb07387.x

S. Cheenpracha, N. B. Vidor, W. Y. Yoshida, J. Davies, and L. C. Chang, sp. L-4-4, Journal of Natural Products, vol.73, issue.5, pp.880-884, 2010.
DOI : 10.1021/np900843b

V. Schroeckh, Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans, Proc. Natl. Acad. Sci. USA, pp.14558-14563, 2009.
DOI : 10.1073/pnas.0901870106

W. G. Weisburg, S. M. Barns, D. A. Pelletier, and D. J. Lane, 16S ribosomal DNA amplification for phylogenetic study., Journal of Bacteriology, vol.173, issue.2, pp.697-703, 1991.
DOI : 10.1128/jb.173.2.697-703.1991

J. G. Caporaso, Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample, Proc. Natl. Acad. Sci. USA 108, pp.4516-4538, 2010.
DOI : 10.1073/pnas.1000080107

S. Altschul, W. Gish, and W. Miller, 15839 | DOi: 10.1038/srep15839 59 Basic Local Alignment Search Tool, J Mol Biol, vol.5, issue.215, pp.403-410, 1990.

S. Courtois, Recombinant Environmental Libraries Provide Access to Microbial Diversity for Drug Discovery from Natural Products, Applied and Environmental Microbiology, vol.69, issue.1, pp.49-55, 2003.
DOI : 10.1128/AEM.69.1.49-55.2003

M. Metsä-ketelä, An efficient approach for screening minimal PKS genes from Streptomyces, FEMS Microbiology Letters, vol.180, issue.1, pp.1-6, 1999.
DOI : 10.1111/j.1574-6968.1999.tb08770.x

H. Matsuyama, K. Kawasaki, I. Yumoto, and O. Shida, Microbacterium kitamiense sp. nov., a new polysaccharide-producing bacterium isolated from the wastewater of a sugar-beet factory, International Journal of Systematic Bacteriology, vol.49, issue.4, pp.1353-1357, 1999.
DOI : 10.1099/00207713-49-4-1353

P. Deetae, H. Spinnler, P. Bonnarme, and S. Helinck, Growth and aroma contribution of Microbacterium foliorum, Proteus vulgaris and Psychrobacter sp. during ripening in a cheese model medium, Applied Microbiology and Biotechnology, vol.8, issue.1, pp.169-177, 2009.
DOI : 10.1007/s00253-008-1805-7

A. F. Braña, H. Fiedler, H. Nava, and G. Blanco, Two Streptomyces Species Producing Antibiotic, Antitumor, and Anti-Inflammatory Compounds Are Widespread Among Intertidal Macroalgae and Deep-Sea Coral Reef Invertebrates from the Central Cantabrian Sea, Microbial Ecology, vol.158, issue.3, pp.512-524, 2015.
DOI : 10.1007/s00248-014-0508-0

V. Bultel-poncé, C. Debitus, A. Blond, and C. Cerceau, Lutoside : an Acyl-l-(Acyi-6' .Mannobiosyi)-3-Giycerol Isolated from the Sponge-associated Bacterium Micrococcus luteus, Science, vol.38, pp.5805-5808, 1997.

O. Barazani and J. Friedman, Is IAA the major root growth factor secreted from plant-growth-mediating bacteria?, Journal of Chemical Ecology, vol.25, issue.10, pp.2397-2406, 1999.
DOI : 10.1023/A:1020890311499

J. Cho, Isolation and Structural Determination of the Antifouling Diketopiperazines from Marine-Derived <i>Streptomyces praecox</i> 291-11, Bioscience, Biotechnology, and Biochemistry, vol.76, issue.6, pp.1116-1121, 2012.
DOI : 10.1271/bbb.110943

T. Iwamoto, FR109615, a new antifungal antibiotic from Streptomyces setonii. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity., The Journal of Antibiotics, vol.43, issue.1, pp.1-7, 1990.
DOI : 10.7164/antibiotics.43.1

S. H. Larsen, L. V. Boeck, F. P. Mertz, J. W. Paschal, and J. L. Occolowitz, 16-Deethylindanomycin (A83094A), a novel pyrrole-ether antibiotic produced by a strain of Streptomyces setonii. Taxonomy, fermentation, isolation and characterization., The Journal of Antibiotics, vol.41, issue.9, pp.1170-1177, 1988.
DOI : 10.7164/antibiotics.41.1170

S. H. Arsen, D. M. Berry, J. W. Paschal, and J. M. Gilliam, 5-Hydroxymethylblasticidin S and blasticidin S from Streptomyces setonii culture A83094., The Journal of Antibiotics, vol.42, issue.3, pp.470-471, 1989.
DOI : 10.7164/antibiotics.42.470

H. Gurtler, Albaflavenone, a sesquiterpene ketone with a zizaene skeleton produced by a streptomycete with a new rope morphology., The Journal of Antibiotics, vol.47, issue.4, pp.434-439, 1994.
DOI : 10.7164/antibiotics.47.434

L. Yan, Antimycin A18 produced by an endophytic Streptomyces albidoflavus isolated from a mangrove plant, The Journal of Antibiotics, vol.61, issue.5, pp.259-261, 2010.
DOI : 10.1038/ja.2005.70

R. N. Roy and S. K. Sen, Fermentation Studies for the Production of Dibutyl Phthalate , an Ester Bioactive Compound from Streptomyces albidoflavus MTCC 3662 Using Low-Priced Substrates, Jordan Journal of Biological Sciences, vol.6, issue.3, pp.177-181, 2013.
DOI : 10.12816/0001530

O. Lapchinskaia, T. Saburova, O. Siniagina, N. Konstantinova, and V. Filicheva, Spontaneous and induced variability in Actinomyces rubiginosohelvolus, a new producer of the antibiotic rubomycin, Antibiotiki, vol.20, pp.1061-1065, 1975.

C. Qi-lei, Z. Zi-han, and W. Lu, Bromoxantholipin, a novel polycyclic xanthone antibiotic produced by Streptomyces flavogriseus SIIA-A02191, Chinese J. Antibiotcs, vol.36, pp.566-570, 2011.

R. Álvarez-Álvarez, Expression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: why a silent cluster is sleeping, Applied Microbiology and Biotechnology, vol.12, issue.32, pp.9451-9463, 2013.
DOI : 10.1007/s00253-013-5148-7

G. R. Pettit, Antineoplastic agents. Part 409: Isolation and structure of montanastatin from a terrestrial actinomycete[1]1Dedicated to the memory of Professor Sir Derek H. R. Barton (1918???1998), a great chemist and friend.1, Bioorganic & Medicinal Chemistry, vol.7, issue.5, pp.895-899, 1999.
DOI : 10.1016/S0968-0896(99)00024-3

K. Shinya, T. Tauchi, T. Morohoshi, T. Ono, . Co et al., GM-95-containing antitumor effect potentiator, combined antitumor preparation and antitumor agent, pp.714-716, 2008.

K. Gebhardt, Endophenazines A-D, new phenazine antibiotics from the Arthropod associated endosymbiont Streptomyces anulatus, J. Antibiot, vol.55, pp.795-800, 2002.

H. Usuki, NBRC 13369, Journal of the American Chemical Society, vol.130, issue.12, pp.4146-4152, 2008.
DOI : 10.1021/ja077641f

D. Sun, S71, Natural Product Research, vol.16, issue.19, pp.1602-1606, 2014.
DOI : 10.6023/cjoc201304039

J. Holmalahti, Production of dihydroabikoviromycin by Streptomyces anulatus: production parameters and chemical characterization of genotoxicity, Journal of Applied Microbiology, vol.85, issue.1, pp.61-68, 1998.
DOI : 10.1046/j.1365-2672.1998.00472.x

X. X. Tian, Isolation and identification of poly-??-(1???4)-linked 3-O-methyl-d-mannopyranose from a hot-water extract of Mycobacterium vaccae, Carbohydrate Research, vol.324, issue.1, pp.38-44, 2000.
DOI : 10.1016/S0008-6215(99)00248-7

M. Izumikawa, T. Kawahara, J. Hwang, M. Takagi, and K. Shin-ya, NBRC 105047, Bioscience, Biotechnology, and Biochemistry, vol.77, issue.3, pp.663-665, 2013.
DOI : 10.1016/S0040-4039(98)01574-3

A. Häberli, C. Bircher, and H. Pfander, Isolation of a New Carotenoid and Two New Carotenoid Glycosides fromCurtobacterium flaccumfaciens pvar poinsettiae, Helvetica Chimica Acta, vol.83, issue.2, pp.328-335, 2000.
DOI : 10.1002/(SICI)1522-2675(20000216)83:2<328::AID-HLCA328>3.0.CO;2-N

A. Osawa, Characterization and Antioxidative Activities of Rare C50 Carotenoids-Sarcinaxanthin, Sarcinaxanthin Monoglucoside, and Sarcinaxanthin Diglucoside-Obtained from Micrococcus yunnanensis, Journal of Oleo Science, vol.59, issue.12, pp.653-659, 2010.
DOI : 10.5650/jos.59.653

X. Zhou, New anti-infective cycloheptadepsipeptide congeners and absolute stereochemistry from the deep sea-derived Streptomyces drozdowiczii SCSIO 10141, Tetrahedron, vol.70, issue.42, pp.7795-7801, 2014.
DOI : 10.1016/j.tet.2014.02.007

M. Hara, Leinamycin, a new antitumor antibiotic from Streptomyces: producing organism, fermentation and isolation, J. Antibiot, vol.42, pp.1768-1774, 1989.

S. Kodai and A. Ninomiya, Isolation of New Thiopeptide Berninamycin E from Streptomyces atroolivaceus, Asian J. Chem, vol.25, pp.490-492, 2013.

A. Shashkov, E. Tul-'skaya, L. Evtushenko, and I. Naumova, A teichoic acid of Nocardioides albus VKM Ac-805(T) cell walls, Biochemistry, vol.64, pp.1305-1309, 1999.

H. Dellweg, Rodaplutin, a new peptidylnuleoside from Nocardioides albus., The Journal of Antibiotics, vol.41, issue.8, pp.1145-1147, 1988.
DOI : 10.7164/antibiotics.41.1145