Thieno[2′,3′:5,6]azepino[2,1- a ]isoindolones from hydroxylactam-alcohols via N -acyliminium ion olefin cyclization

Pascal Pigeon (1) , Mohamed Othman (1) , Bernard Decroix (1)

1 ULH - Université Le Havre Normandie

A one pot synthesis of thienoazepinoisoindolones from the reaction of hydroxylactam-alcohols, under acidic treatment, is described via an N-acyliminium olefin cyclization.

Domaines: Chimie

Pascal Pigeon, Mohamed Othman, Bernard Decroix. Thieno[2′,3′:5,6]azepino[2,1- a ]isoindolones from hydroxylactam-alcohols via N -acyliminium ion olefin cyclization. Journal of Heterocyclic Chemistry, 2001, 38 (1), pp.35 - 39. ⟨10.1002/jhet.5570380105⟩. ⟨hal-01230407⟩