Highly sensitive electrochemical biosensor for bisphenol A detection based on a diazonium-functionalized boron-doped diamond electrode modified with a multi-walled carbon nanotube-tyrosinase hybrid film

Abstract : A highly sensitive electrochemical biosensor for the detection of Bisphenol A (BPA) in water has been developed by immobilizing tyrosinase onto a diazonium-functionalized boron doped diamond electrode (BDD) modified with multi-walled carbon nanotubes (MWCNTs). The fabricated biosensor exhibits ex. cellent electroactivity towards o-quinone, a product of this enzymatic reaction of BPA oxidation catalyzed by tyrosinase. The developed BPA biosensor displays a large linear range from 0.01 nM to 100 nM, with a detection limit (LOD) of 10 pM. The feasibility of the proposed biosensor has been demonstrated on BPA spiked water river samples. Therefore, it could be a promising and reliable analytical tool for on-site monitoring of BPA in waste water.
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https://hal.archives-ouvertes.fr/hal-01229808
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Submitted on : Tuesday, November 17, 2015 - 11:23:19 AM
Last modification on : Wednesday, April 3, 2019 - 1:31:23 AM

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Nedjla Zehani, Philippe Fortgang, Mohamed Saddek Lachgar, Abdoullatif Baraket, Madjid Arab, et al.. Highly sensitive electrochemical biosensor for bisphenol A detection based on a diazonium-functionalized boron-doped diamond electrode modified with a multi-walled carbon nanotube-tyrosinase hybrid film. Biosensors and Bioelectronics, Elsevier, 2015, 74, pp.830-835. 〈10.1016/j.bios.2015.07.051〉. 〈hal-01229808〉

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