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From medical imaging to numerical simulations

Abstract : In the last 20 years there have been lots of progress in 3D medical imaging (such as Magnetic Resonance Imaging, MRI, and X-ray Computed Tomography, CT) and in particular in modalities to visualise vascular structures. The resulting images have been successfully used in various clinical applications, in particular for cerebrovascular pathologies (e.g., neurosurgery planning; stenoses, aneurysm or thrombosis quantification; arteriovenous malformation detection and follow-up, etc.). The complexity of the processing and analysis of these images (size, information vs noise, artifacts, etc) led to the development of imaging tools such as vessel filtering, segmentation and quantification. There is however, until now, no database of synthetic images and associated ground-truths (segmented data) available in cerebrovascular images contrary to morphological brain image analysis (e.g. brainweb). In the ANR Vivabrain project, we combine the skills of several communities: computer science, applied mathematics, biophysics, and medicine to remedy the aforementioned observation. In particular we focus on complex multi-disciplinary problems such as (i) the handling of inter-individual cerebrovascular variability, (ii) the generation of computational meshes, (iii) the simulation of blood flows in the complete cerebrovascular system 3D+time (3D+t) including calibration and validation and (iv) the accurate simulation of the physical processes involved in MRA acquisition sequences in order to finally obtain realistic virtual angiographic images.
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Contributor : Christophe Prud'Homme Connect in order to contact the contributor
Submitted on : Monday, November 2, 2015 - 8:35:08 AM
Last modification on : Tuesday, October 19, 2021 - 11:13:17 PM
Long-term archiving on: : Wednesday, February 3, 2016 - 10:30:37 AM


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  • HAL Id : hal-01223120, version 1



Christophe Prud'Homme, Vincent Chabannes, Marcela Szopos, Alexandre Ancel, Julien Jomier. From medical imaging to numerical simulations. Advanced technologies and treatments for Glaucoma, Oct 2015, Milano, Italy. ⟨hal-01223120⟩



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