Longitudinal and circumferential mechanical behavior of human cerebral artery

Dominique Ambard (1, 2) , Omer Eker (3) , Simon Le Floc’h (1, 2) , Vincent Costalat (3) , Mathieu Sanchez (1, 2) , Franck Jourdan (1, 2)

1 LMGC - Laboratoire de Mécanique et Génie Civil
2 BIOTIC - Biomécanique des Interactions et de l'Organisation des Tissus et des Cellules
3 Service de Neuroradiologie, Hôpital Gui de Chauliac, CHRU Montpellier

The prevalence of unruptured intracranial aneurysms in the general population, as reported by a recent review [Wardlaw, 2000], ranges between 3% and 6.6%. However, the incidence of ruptured aneurysms is low, with approximately 0.5% per year, suggesting that very few aneurysms rupture. Clearly, new patient-specific indexes predicting aneurysm risk of rupture should be proposed, in order to guide therapeutic decision for unruptured aneurysm. Previously, we showed that aneurismal pulsatility might be a relevant patient-specific predictor of aneurysm risk of rupture [Sanchez, 2013], as the pulsability showed to provide information on the degradation of the mechanical properties of ruptured aneurism tissue. However, the biomechanical properties of healthy arteries of circle of Willis are poorly reported. In this study, we attempted to identify the biomechanical behavior of healthy intracranial artery taken from autopsied subjects.

Domaines: Matériaux; Biomécanique [physics.med-ph]; Mécanique des matériaux [physics.class-ph]; Mécanique [physics.med-ph]

Dominique Ambard, Omer Eker, Simon Le Floc’h, Vincent Costalat, Mathieu Sanchez, et al.. Longitudinal and circumferential mechanical behavior of human cerebral artery. 21st congress of the european society of biomechanics, Jul 2015, Prague, Czech Republic. ⟨hal-01219454⟩