C. Arias and B. Murray, The rise of the Enterococcus: beyond vancomycin resistance, Nature Reviews Microbiology, vol.5, issue.4, pp.266-278, 2012.
DOI : 10.1038/nrmicro2761

P. Reynolds, Structure, biochemistry and mechanism of action of glycopeptide antibiotics, European Journal of Clinical Microbiology & Infectious Diseases, vol.157, issue.Supplement A, pp.943-950, 1989.
DOI : 10.1007/BF01967563

F. Depardieu, I. Podglajen, R. Leclercq, E. Collatz, and P. Courvalin, Modes and Modulations of Antibiotic Resistance Gene Expression, Clinical Microbiology Reviews, vol.20, issue.1, pp.79-114, 2007.
DOI : 10.1128/CMR.00015-06

D. Boyd, B. Willey, D. Fawcett, N. Gillani, and M. Mulvey, Molecular Characterization of Enterococcus faecalis N06-0364 with Low-Level Vancomycin Resistance Harboring a Novel D-Ala-D-Ser Gene Cluster, vanL, Antimicrobial Agents and Chemotherapy, vol.52, issue.7, pp.2667-2672, 2008.
DOI : 10.1128/AAC.01516-07

F. Lebreton, F. Depardieu, N. Bourdon, M. Fines-guyon, P. Berger et al., D-Ala-D-Ser VanN-Type Transferable Vancomycin Resistance in Enterococcus faecium, Antimicrobial Agents and Chemotherapy, vol.55, issue.10, pp.4606-4612, 2011.
DOI : 10.1128/AAC.00714-11

X. Xu, D. Lin, G. Yan, X. Ye, S. Wu et al., vanM, a New Glycopeptide Resistance Gene Cluster Found in Enterococcus faecium, Antimicrobial Agents and Chemotherapy, vol.54, issue.11, pp.4643-4647, 2010.
DOI : 10.1128/AAC.01710-09

F. Depardieu, P. Courvalin, and T. Msadek, A six amino acid deletion, partially overlapping the VanSB G2 ATP-binding motif, leads to constitutive glycopeptide resistance in VanB-type Enterococcus faecium, Molecular Microbiology, vol.45, issue.3, pp.1069-1083, 2003.
DOI : 10.1046/j.1365-2958.2003.03771.x

F. Depardieu, P. Courvalin, and A. Kolb, BM4524, Molecular Microbiology, vol.45, issue.2, pp.550-564, 2005.
DOI : 10.1111/j.1365-2958.2005.04706.x

G. Wright, T. Holman, and C. Walsh, Purification and characterization of VanR and the cytosolic domain of VanS: A two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147, Biochemistry, vol.32, issue.19, pp.5057-5063, 1993.
DOI : 10.1021/bi00070a013

M. Arthur, F. Depardieu, G. Gerbaud, M. Galimand, R. Leclercq et al., The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction., Journal of Bacteriology, vol.179, issue.1, pp.97-106, 1997.
DOI : 10.1128/jb.179.1.97-106.1997

F. Depardieu, M. Bonora, P. Reynolds, and P. Courvalin, The vanG glycopeptide resistance operon from Enterococcus faecalis revisited, Molecular Microbiology, vol.32, issue.3, pp.931-948, 2003.
DOI : 10.1046/j.1365-2958.2003.03737.x

N. Ruiz, B. Falcone, D. Kahne, and T. Silhavy, Chemical Conditionality, Cell, vol.121, issue.2, pp.307-317, 2005.
DOI : 10.1016/j.cell.2005.02.014
URL : http://doi.org/10.1016/j.cell.2005.02.014

T. Holman, Z. Wu, B. Wanner, and C. Walsh, Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium, Biochemistry, vol.33, issue.15, pp.4625-4631, 1994.
DOI : 10.1021/bi00181a024

G. Koudelka and C. Lam, Differential recognition of OR1 and OR3 by bacteriophage 434 repressor and Cro, J Biol Chem, vol.268, pp.23812-23817, 1993.

M. Cervin, R. Lewis, J. Brannigan, and G. Spiegelman, The Bacillus subtilis regulator SinR inhibits spoIIG promoter transcription in vitro without displacing RNA polymerase, Nucleic Acids Research, vol.26, issue.16, pp.3806-3812, 1998.
DOI : 10.1093/nar/26.16.3806

J. Newman, C. Rodrigues, and R. Lewis, Molecular Basis of the Activity of SinR Protein, the Master Regulator of Biofilm Formation in Bacillus subtilis, Journal of Biological Chemistry, vol.288, issue.15, p.23430750, 2013.
DOI : 10.1074/jbc.M113.455592

K. Makino, H. Shinagawa, M. Amemura, T. Kawamoto, M. Yamada et al., Signal transduction in the phosphate regulon of Escherichia coli involves phosphotransfer between PhoR and PhoB proteins, Journal of Molecular Biology, vol.210, issue.3, pp.551-559, 1989.
DOI : 10.1016/0022-2836(89)90131-9

M. Ansaldi, G. Simon, M. Lepelletier, and V. Mejean, The TorR High-Affinity Binding Site Plays a Key Role in Both torR Autoregulation and torCAD Operon Expression in Escherichia coli, Journal of Bacteriology, vol.182, issue.4, pp.961-966, 2000.
DOI : 10.1128/JB.182.4.961-966.2000

M. Igo, A. Ninfa, J. Stock, and T. Silhavy, Phosphorylation and dephosphorylation of a bacterial transcriptional activator by a transmembrane receptor., Genes & Development, vol.3, issue.11, pp.1725-1734, 1989.
DOI : 10.1101/gad.3.11.1725

E. Kamberov, M. Atkinson, P. Chandran, and A. Ninfa, Effect of mutations in Escherichia coli glnL (ntrB), encoding nitrogen regulator II (NRII or NtrB), on the phosphatase activity involved in bacterial nitrogen regulation, J Biol Chem, vol.269, pp.28294-28299, 1994.

M. Arthur, F. Depardieu, and P. Courvalin, Regulated interactions between partner and non-partner sensors and response regulators that control glycopeptide resistance gene expression in enterococci, Microbiology, vol.145, issue.8, pp.1849-1858, 1999.
DOI : 10.1099/13500872-145-8-1849

M. Ogura, H. Yoshikawa, and T. Chibazakura, Regulation of the Response Regulator Gene degU through the Binding of SinR/SlrR and Exclusion of SinR/SlrR by DegU in Bacillus subtilis, Journal of Bacteriology, vol.196, issue.4, pp.873-881, 2014.
DOI : 10.1128/JB.01321-13

M. Mittal, K. Pechter, S. Picossi, H. Kim, K. Kerstein et al., Dual role of CcpC protein in regulation of aconitase gene expression in Listeria monocytogenes and Bacillus subtilis, Microbiology, vol.159, issue.Pt_1, pp.68-76, 2013.
DOI : 10.1099/mic.0.063388-0

B. Belitsky, Indirect Repression by Bacillus subtilis CodY via Displacement of the Activator of the Proline Utilization Operon, Journal of Molecular Biology, vol.413, issue.2, pp.321-336, 2011.
DOI : 10.1016/j.jmb.2011.08.003

A. Mitrophanov and E. Groisman, Signal integration in bacterial two-component regulatory systems, Genes & Development, vol.22, issue.19, pp.2601-2611, 2008.
DOI : 10.1101/gad.1700308

D. Buelow and T. Raivio, Three (and more) component regulatory systems - auxiliary regulators of bacterial histidine kinases, Molecular Microbiology, vol.70, issue.7, pp.547-566, 2010.
DOI : 10.1111/j.1365-2958.2009.06982.x

M. Foucault, F. Depardieu, P. Courvalin, and C. Grillot-courvalin, Inducible expression eliminates the fitness cost of vancomycin resistance in enterococci, Proceedings of the National Academy of Sciences, vol.107, issue.39, pp.16964-16969, 2010.
DOI : 10.1073/pnas.1006855107
URL : https://hal.archives-ouvertes.fr/pasteur-00552977

F. Studier and B. Moffatt, Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes, Journal of Molecular Biology, vol.189, issue.1, pp.113-130, 1986.
DOI : 10.1016/0022-2836(86)90385-2

K. Amrein, B. Takacs, M. Stieger, J. Molnos, N. Flint et al., Purification and characterization of recombinant human p50csk protein-tyrosine kinase from an Escherichia coli expression system overproducing the bacterial chaperones GroES and GroEL., Proceedings of the National Academy of Sciences, vol.92, issue.4, pp.1048-1052, 1995.
DOI : 10.1073/pnas.92.4.1048

S. Brinster, S. Furlan, and P. Serror, C-Terminal WxL Domain Mediates Cell Wall Binding in Enterococcus faecalis and Other Gram-Positive Bacteria, Journal of Bacteriology, vol.189, issue.4, pp.1244-1253, 2007.
DOI : 10.1128/JB.00773-06

R. Kay and J. Mcpherson, Hybrid pUC vectors for addition of new restriction enzyme sites to the ends of DNA fragments (1977) A new method for sequencing DNA, Nucleic Acids Res Proc Natl Acad Sci, vol.15, issue.74, pp.560-564, 1987.

A. Jacob and S. Hobbs, Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes, J Bacteriol, vol.117, pp.360-372, 1974.

A. Maxam and W. Gilbert, A new method for sequencing DNA., Proceedings of the National Academy of Sciences, vol.74, issue.2, pp.560-564, 1977.
DOI : 10.1073/pnas.74.2.560

M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Analytical Biochemistry, vol.72, issue.1-2, pp.248-254, 1976.
DOI : 10.1016/0003-2697(76)90527-3

A. Chastanet, J. Fert, and T. Msadek, Comparative genomics reveal novel heat shock regulatory mechanisms in Staphylococcus aureus and other Gram-positive bacteria, Molecular Microbiology, vol.183, issue.4, pp.1061-1073, 2003.
DOI : 10.1046/j.1365-2958.2003.03355.x

E. Maguin, H. Prevost, S. Ehrlich, and A. Gruss, Efficient insertional mutagenesis in lactococci and other gram-positive bacteria., Journal of Bacteriology, vol.178, issue.3, pp.931-935, 1996.
DOI : 10.1128/jb.178.3.931-935.1996

S. Brockbank and P. Barth, Cloning, sequencing, and expression of the DNA gyrase genes from Staphylococcus aureus., Journal of Bacteriology, vol.175, issue.11, pp.3269-3277, 1993.
DOI : 10.1128/jb.175.11.3269-3277.1993

M. Arthur, F. Depardieu, P. Reynolds, and P. Courvalin, Quantitative analysis of the metabolism of soluble cytoplasmic peptidoglycan precursors of glycopeptide-resistant enterococci, Molecular Microbiology, vol.21, issue.1, pp.33-44, 1996.
DOI : 10.1046/j.1365-2958.1996.00617.x

F. Lebreton, W. Van-schaik, A. Mcguire, P. Godfrey, A. Griggs et al., Emergence of Epidemic Multidrug-Resistant Enterococcus faecium from Animal and Commensal Strains, mBio, vol.4, issue.4, 2013.
DOI : 10.1128/mBio.00534-13