C. Andrews-pfannkocj, D. W. Fadrosh, J. Thorpe, and S. J. Williamson, Hydroxyapatite-mediated separation of double-stranded DNA, single-stranded DNA and RNA genomes from natural viral assemblages, Appl. Environ. Microbiol, pp.76-5039, 2010.

H. Autefage, R^ ole ost eoinducteur d'un rev^ etement d'hydroxyapatite carbonat ee nanocristalline sur des c eramiques de phosphate de calcium biphasique, 2009.

L. Bertinetti, C. Drouet, C. Combes, C. Rey, A. Tampieri et al., Surface Characteristics of Nanocrystalline Apatites: Effect of Mg Surface Enrichment on Morphology, Surface Hydration Species, and Cationic Environments, Langmuir, vol.25, issue.10, pp.5647-5654, 2009.
DOI : 10.1021/la804230j

S. Cazalbou, C. Combes, D. Eichert, M. Rey, and . Glimcher, Poorly crystalline apatites: evolution and maturation in vitro and in vivo, Journal of Bone and Mineral Metabolism, vol.22, issue.4, pp.22-310, 2004.
DOI : 10.1007/s00774-004-0488-0

S. Cazalbou, D. Eichert, X. Ranz, C. Drouet, C. Combes et al., Ion exchanges in apatites for biomedical application, Journal of Materials Science: Materials in Medicine, vol.29, issue.5, p.16, 2005.
DOI : 10.1007/s10856-005-6979-2

C. Drouet, M. Carayon, C. Combes, and C. Rey, Surface enrichment of biomimetic apatites with biologically-active ions Mg2+ and Sr2+: A preamble to the activation of bone repair materials, Materials Science and Engineering: C, vol.28, issue.8, pp.1544-1550, 2008.
DOI : 10.1016/j.msec.2008.04.011

D. Eichert, H. Sfihi, C. Combes, and C. Rey, Specific Characteristics of Wet Nanocrystalline Apatites. Consequences on Biomaterials and Bone Tissue, Key Engineering Materials, vol.254, issue.256, pp.254-256, 2004.
DOI : 10.4028/www.scientific.net/KEM.254-256.927
URL : https://hal.archives-ouvertes.fr/hal-00162414

D. Eichert, C. Combes, C. Drouet, and C. Rey, Formation and Evolution of Hydrated Surface Layers of Apatites, Key Engineering Materials, vol.284, issue.286, pp.284-286, 2005.
DOI : 10.4028/www.scientific.net/KEM.284-286.3
URL : https://hal.archives-ouvertes.fr/hal-00474890

J. C. Elliott, Structure and Chemistry of the Apatites and Other Calcium Orthophosphates, 1994.

F. Errassifi, A. Menbaoui, H. Autefage, L. Benaziz, S. Ouizat et al., Adsorption on Apatitic Calcium Phosphates: Applications to Drug Delivery, Ceram. Trans. (Adv. Bioceram. Biotechnol.), vol.34, issue.4, pp.159-174, 2010.
DOI : 10.1002/9780470909898.ch16

D. Grossin, S. Rollin-martinet, C. Estournes, F. Rossignol, E. Champion et al., Biomimetic apatite sintered at very low temperature by spark plasma sintering: Physico-chemistry and microstructure aspects, Acta Biomaterialia, vol.6, issue.2, pp.577-585, 2010.
DOI : 10.1016/j.actbio.2009.08.021
URL : https://hal.archives-ouvertes.fr/hal-00449219

J. Gustavsson, M. P. Ginebra, E. Engel, and J. , Ion reactivity of calcium-deficient hydroxyapatite in standard cell culture media, Acta Biomaterialia, vol.7, issue.12, pp.4242-4252, 2011.
DOI : 10.1016/j.actbio.2011.07.016

J. Hsu, J. L. Fox, W. I. Higuchi, G. L. Powell, M. Otsuka et al., Metastable Equilibrium Solubility Behavior of Carbonated Apatites, Journal of Colloid and Interface Science, vol.167, issue.2, 1994.
DOI : 10.1006/jcis.1994.1376

H. M. Kim, C. Rey, and M. J. Glimcher, Isolation of calcium-phosphate crystals of bone by non-aqueous methods at low temperature, Journal of Bone and Mineral Research, vol.134, issue.01, 1995.
DOI : 10.1002/jbmr.5650101021

T. Kokubo and H. Takadama, How useful is SBF in predicting in vivo bone bioactivity?, Biomaterials, vol.27, issue.15, pp.2907-2915, 2006.
DOI : 10.1016/j.biomaterials.2006.01.017

K. Matsunaga, Theoretical Defect Energetics in Calcium Phosphate Bioceramics, Journal of the American Ceramic Society, vol.93, issue.1, pp.1-14, 2010.
DOI : 10.1111/j.1551-2916.2009.03485.x

C. Mukherjee, F. Huang, K. Guerra, E. Wang, and . Oldfield, Thermodynamics of Bisphosphonates Binding to Human Bone: A Two-Site Model, Journal of the American Chemical Society, vol.131, issue.24, pp.131-8374, 2009.
DOI : 10.1021/ja902895p

P. Pascaud, R. Bareille, C. Bourget, J. Am-ed-ee, C. Rey et al., Interaction between a bisphosphonate, tiludronate and nanocrystalline apatite: in vitro viability and proliferation of HOP and HBMSC cells, Biomed. Mater, vol.7054108, issue.05410875, pp.1748-6041, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00863280

P. Pascaud, P. Gras, Y. Coppel, C. Rey, and S. Sarda, Interaction between a Bisphosphonate, Tiludronate, and Biomimetic Nanocrystalline Apatites, Langmuir, vol.29, issue.7, pp.2224-2232, 2013.
DOI : 10.1021/la3046548

C. Rey, C. Combes, C. Drouet, A. Lebugle, H. Sfihi et al., Nanocrystalline apatites in biological systems: characterisation, structure and properties, Materialwissenschaft und Werkstofftechnik, vol.27, issue.86, pp.996-1002, 2007.
DOI : 10.1002/mawe.200700229

C. Rey, C. Combes, C. Drouet, H. Sfihi, and A. Barroug, Physico-chemical properties of nanocrystalline apatites: Implications for biominerals and biomaterials, Materials Science and Engineering: C, vol.27, issue.2, 2007.
DOI : 10.1016/j.msec.2006.05.015
URL : https://hal.archives-ouvertes.fr/hal-00164914

C. Rey, C. Combes, C. Drouet, and M. J. Glimcher, Bone mineral: update on chemical composition and structure, Osteoporosis Int, 2009.

C. Rey, C. Combes, C. Drouet, and D. Grossin, Bioactive Ceramics: Physical Chemistry, Comprehensive Biomaterials, pp.187-221, 2011.
DOI : 10.1016/B978-0-08-055294-1.00178-1

R. E. Riman, W. L. Suhanek, K. Byrappa, C. W. Chen, P. Shuk et al., Solution synthesis of hydroxyapatite designer particulates, Solid State Ionics, vol.151, issue.1-4, pp.394-402, 2002.
DOI : 10.1016/S0167-2738(02)00545-3

H. Sfihi and C. Rey, 1-D and 2-D Double Heteronuclear Magnetic Resonance Study of the Local Structure of Type B Carbonate Fluoroapatite, Magnetic Resonance in Colloid and Interface Science, pp.409-418, 2002.
DOI : 10.1007/978-94-010-0534-0_36

N. Vandecandelaere, C. Rey, and C. Drouet, Biomimetic apatite-based biomaterials: on the critical impact of synthesis and post-synthesis parameters, Journal of Materials Science: Materials in Medicine, vol.27, issue.11, pp.2593-2606, 2012.
DOI : 10.1007/s10856-012-4719-y

Y. Wang, T. Azaïs, M. Robin, A. Vall-ee, C. Catania et al., The predominant role of collagen??in the nucleation, growth, structure??and orientation??of??bone apatite, Nature Materials, vol.41, issue.8, pp.724-733, 2012.
DOI : 10.1038/nmat3362
URL : https://hal.archives-ouvertes.fr/hal-01461430

R. M. Wilson, S. E. Dowker, and J. C. Elliott, Rietveld refinements and spectroscopic structural studies of a Na-free carbonate apatite made by hydrolysis of monetite, Biomaterials, vol.27, issue.27, pp.4682-4692, 2005.
DOI : 10.1016/j.biomaterials.2006.04.033

R. M. Wilson, J. C. Elliot, S. E. Dowker, and L. M. Rodriguez-lorenzo, Rietveld refinements and spectroscopic studies of the structure of Ca-deficient apatite, Biomaterials, vol.26, issue.11, pp.1317-1327, 2005.
DOI : 10.1016/j.biomaterials.2004.04.038

S. D. Cazalbou-obtained-her-ph, ) at the INP in Toulouse Her research activities focused on bone mineral and its reactivity She was particularly interested in cationic substitutions involving apatitic nanocrystals similar to bone mineral. She also worked on a treatment using strontium to treat the effect of osteoporosis . After her Ph.D., she continued on the development of bioactive mineral coatings for metal and ceramic prostheses. These results are being used and marketed by companies in the field of biomaterials she joined the faculty of pharmacy in Toulouse where she obtained a position as professor assistant. She joined, by this way, the " Phosphates, Pharmacotechnics, Biomaterials " research group of the CIRIMAT Carnot Institute in Toulouse, where she has begun her research activities. Currently, her teaching activities focus on the formulation and development of medicine while her research activities focus on the formulation of biomaterials with therapeutic activity, the percolation theory used as part of formulation and more generally, on the influence of physico-chemical and morphological parameters on the ability of biomaterials to release a containing drug, 2000.