The DIDGI® System

Olivia Ménard (1) , Didier Dupont (1) , Daniel Picque (2)

1 STLO - Science et Technologie du Lait et de l'Oeuf
2 GMPA - Génie et Microbiologie des Procédés Alimentaires

A simple two-compartment in vitro dynamic gastrointestinal digestion system allowing the study of the disintegration of food during digestion has been recently developed at INRA. As a first application, it has been used for understanding the mechanisms of infant formula disintegration in the infant gastrointestinal tract. The developed system was validated by comparing the kinetics of proteolysis obtained in vitro towards in vivo data collected on piglets. Results showed a good correlation between in vitro and in vivo data and prove the physiological relevance of the newly developed system.

Mots clés: digestion; digesteur; santé humaine; peptide bioactif

Domaines: Alimentation et Nutrition; Microbiologie et Parasitologie; Ingénierie des aliments

Olivia Ménard, Didier Dupont, Daniel Picque. The DIDGI® System. The Impact of Food Bioactives on Health in vitro and ex vivo models, Springer International Publishing, 2015, 978-3-319-15791-7. ⟨10.1007/978-3-319-16104-4⟩. ⟨hal-01195520⟩