Discovering lactic acid bacteria by genomics

Todd Klaenhammer (1) , Eric Altermann (2) , Fabrizio Arigoni (3) , Alexandre Bolotine (4) , Fred Breidt (5) , Jeffrey Broadbent (6) , Raul Cano (7) , Stephane Chaillou (8) , Josef Deutscher (9) , Mike Gasson (10) , Maarten van de Guchte (4) , Jean Guzzo (11) , Axel Hartke (12) , Trevor Hawkins (13) , Pascal Hols (14) , Robert Hutkins (15) , Michiel Kleerebezem (16) , Jan Kok (17) , Oscar Kuipers (17) , Mark Lubbers (18) , Emmanuelle Maguin (4) , Larry Mckay (19) , David Mills (20) , Arjen Nauta (21) , Ross Overbeek (22) , Herman Pel (23) , David Pridmore (3) , Milton Saier (24) , Douwe van Sinderen (25) , Alexei Sorokine (4) , James Steele (26) , Daniel O'Sullivan (19) , Willem de Vos (16) , Bart Weimer (27) , Monique Zagorec (8) , Roland Siezen (16, 28)

1 Department of Science
2 Department of Food Science
3 Nestlé Research Center | Centre de recherche Nestlé [Lausanne]
4 UGM - Unité de recherche Génétique Microbienne
5 Department of Food Science - USDA Agricultural Research Service
6 Department of Nutrition and Food Science
7 EBI - Environmental Biotechnology Institute [San Luis Obispo]
8 UFLEC - Unité de recherche Flore Lactique et Environnement Carné
9 UGMC - Génétique Moléculaire et Cellulaire
10 Institute of Food Research [Norwich]
11 Microbiologie
12 LME - Laboratoire de Microbiologie de l’Environnement
13 Joint Genome Institute Production Genomic Facility
14 Unité de Génétique
15 Department of Food Science and Technology
16 Wageningen Center for Food Sciences
17 Department of Molecular Genetics
18 Fonterra Research Centre
19 Department of Food Science and Nutrition
20 Department of Viticulture
21 corporate Research FCDF
22 Integrated Genomics Inc.
23 DSM Food Specialties
24 UC - University of California
25 Department of Microbiology
26 Department of Food Science
27 Department of Nutrition and Food Sciences
28 Center for Molecular and Biomolecular Informatics

This review summarizes a collection of lactic acid bacteria that are now undergoing genomic sequencing and analysis. Summaries are presented on twenty different species, with each overview discussing the organisms fundamental and practical significance, environmental habitat, and its role in fermentation, bioprocessing, or probiotics. For those projects where genome sequence data were available by March 2002, summaries include a listing of key statistics and interesting genomic features. These efforts will revolutionize our molecular view of Gram-positive bacteria, as up to 15 genomes from the low GC content lactic acid bacteria are expected to be available in the public domain by the end of 2003. Our collective view of the lactic acid bacteria will be fundamentally changed as we rediscover the relationships and capabilities of these organisms through genomics.

Mots clés: Brevibacterium; Bifidobacterium; Propionibacterium; Oenococcus; Leuconostoc; Pediococcus; Streptococcus; Lactobacillus; Lactococcus; health; food; Gram-positive bacteria; genomics; lactic acid bacteria

Domaines: Sciences du Vivant [q-bio]

Todd Klaenhammer, Eric Altermann, Fabrizio Arigoni, Alexandre Bolotine, Fred Breidt, et al.. Discovering lactic acid bacteria by genomics. Antonie van Leeuwenhoek, 2002, 82 (1-4), pp.29-58. ⟨hal-01190023⟩