Nanozeolite-LTL with Gd(III) deposited in the large and Eu(III) in the small cavities as a magnetic resonance optical imaging probe.

Abstract : The immense structural diversity of more than 200 known zeolites is the basis for the wide variety of applications of these fascinating materials ranging from catalysis and molecular filtration to agricultural uses. Despite this versatility, the potential of zeolites in medical imaging has not yet been much exploited. In this work a novel strategy is presented to selectively deposit different ions into distinct framework locations of zeolite-LTL (Linde type L) and it is demonstrated that the carefully ion-exchanged Gd/Eu-containing nanocrystals acquire exceptional magnetic properties in combination with enhanced luminescence. This smart exploitation of the framework structure yields the highest relaxivity density (13.7 s(-1) L g(-1) at 60 MHz and 25 °C) reported so far for alumosilicates, rendering these materials promising candidates for the design of dual magnetic resonance/optical imaging probes, as demonstrated in preliminary phantom studies.
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Journal articles
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https://hal.archives-ouvertes.fr/hal-01179402
Contributor : Isabelle Frapart <>
Submitted on : Wednesday, July 22, 2015 - 2:17:19 PM
Last modification on : Thursday, May 2, 2019 - 3:20:06 PM

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  • HAL Id : hal-01179402, version 1
  • PUBMED : 24523192

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Florian Mayer, Wuyuan Zhang, Thomas Brichart, Olivier Tillement, Célia S Bonnet, et al.. Nanozeolite-LTL with Gd(III) deposited in the large and Eu(III) in the small cavities as a magnetic resonance optical imaging probe.. Chemistry - A European Journal, Wiley-VCH Verlag, 2014, 20 (12), pp.3358-3364. ⟨hal-01179402⟩

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