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In Vivo NIRS Monitoring in Pig Spinal Cord Tissues

Olivier Tsiakaka 1, * Mehdi Terosiet 2 Olivier Romain 2 Aymeric Histace 2 Habib Benali 3 Pierre-François Pradat 4, 3 Farouk Vallette 1 Michaël Feher 1 Sylvain Feruglio 1 
* Corresponding author
1 SYEL - Systèmes Electroniques
LIP6 - Laboratoire d'Informatique de Paris 6
2 ASTRE [Cergy-Pontoise]
ETIS - UMR 8051 - Equipes Traitement de l'Information et Systèmes
Abstract : Little is known about the processes occurring after Spinal Cord damage. Whether permanent or recoverable, those processes have not been precisely characterized because their mechanism is complex and information on the functioning of this organ are partial. This study demonstrates the feasibility of Spinal Cord activity monitoring using Near Infra-Red Spectroscopy in a pig animal model. This animal has been chosen because of its comparable size and its similarities with humans. In the first step, optical characterization of the Spinal Cord tissues was performed in different conditions using a spectrophotometer. Optical Density was evaluated between 3.5 and 6.5 in the [500; 950] nm range. Secondly, adapted light sources with custom probes were used to observe autonomic functions in the spine. Results on the measured haemodynamics at rest and under stimulation show in real time the impact of a global stimulus on a local section of the Spinal Cord. The photoplethysmogram signal of the Spinal Cord showed low AC-to-DC ratio (below to 1 %).
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https://hal.archives-ouvertes.fr/hal-01162223
Contributor : Aymeric Histace Connect in order to contact the contributor
Submitted on : Tuesday, June 9, 2015 - 8:50:39 PM
Last modification on : Friday, August 5, 2022 - 2:45:59 PM

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Olivier Tsiakaka, Mehdi Terosiet, Olivier Romain, Aymeric Histace, Habib Benali, et al.. In Vivo NIRS Monitoring in Pig Spinal Cord Tissues. EMBC 2015 - 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Aug 2015, Milan, Italy. pp.4262-4265, ⟨10.1109/EMBC.2015.7319336⟩. ⟨hal-01162223⟩

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