Rapid Synthesis of Unsymmetrical Sulforhodamines Through Nucleophilic Amination of a Monobrominated Sulfoxanthene Dye

Arnaud Chevalier (1) , Kévin Renault (1) , Frederic Boschetti , Pierre-Yves Renard (1) , Anthony Romieu (1)

1 COBRA - Chimie Organique et Bioorganique : Réactivité et Analyse

Simplicity and diversity! A range of primary and secondary functionalized amines were easily introduced onto a sulfoxanthene dye through simple metal‐free SNAr reactions to provide original sulforhodamine fluorophores with promising properties.

Domaines: Chimie organique; Chemo-informatique; Chimie thérapeutique; Chimie théorique et/ou physique

Arnaud Chevalier, Kévin Renault, Frederic Boschetti, Pierre-Yves Renard, Anthony Romieu. Rapid Synthesis of Unsymmetrical Sulforhodamines Through Nucleophilic Amination of a Monobrominated Sulfoxanthene Dye. European Journal of Organic Chemistry, 2015, 2015 (1), pp.152-165. ⟨10.1002/ejoc.201403165⟩. ⟨hal-01150274⟩