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Measurement of cell traction forces with ImageJ.

Abstract : The quantification of cell traction forces requires three key steps: cell plating on a deformable substrate, measurement of substrate deformation, and the numerical estimation of the corresponding cell traction forces. The computing steps to measure gel deformation and estimate the force field have somehow limited the adoption of this method in cell biology labs. Here we propose a set of ImageJ plug-ins so that every lab equipped with a fluorescent microscope can measure cell traction forces.
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Contributor : Jacqueline Martin-Laffon <>
Submitted on : Wednesday, April 15, 2015 - 3:19:07 PM
Last modification on : Wednesday, July 15, 2020 - 9:28:03 AM




Jean-Louis Martiel, Aldo Leal, Laetitia Kurzawa, Martial Balland, Irene Wang, et al.. Measurement of cell traction forces with ImageJ.. Paluch, E.K. Methods in Cell Biology, 125, Elsevier, pp.269-87, 2015, Biophysical methods in cell biology, 978-0-12-801103-4. ⟨10.1016/bs.mcb.2014.10.008⟩. ⟨hal-01142591⟩



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