Awakening of a Ferrous Complex’s Electronic Spin in an Aqueous Solution Induced by a Chemical Stimulus

Fayçal Touti (1) , Philippe Maurin (1) , Laurence Canaple (2) , Olivier Beuf (3) , Jens Hasserodt (1)

1 LC - Laboratoire de Chimie - UMR5182
2 IGFL - Institut de Génomique Fonctionnelle de Lyon
3 RMN et optique : De la mesure au biomarqueur

A low-spin, macrocyclic iron(II) complex in an aqueous solution responds to the addition of a chemical reactant (dithionite) by transformation into a high-spin complex, detectable by measurement of the longitudinal relaxation time (T1) of surrounding water hydrogen nuclear spins. The initial compound does not modify T1 of pure water at concentrations as high as 4 mM. The response is pH-dependent, and the complex is robust at a variety of conditions.

Domaines: Chimie; Chimie thérapeutique; Chimie de coordination

Fayçal Touti, Philippe Maurin, Laurence Canaple, Olivier Beuf, Jens Hasserodt. Awakening of a Ferrous Complex’s Electronic Spin in an Aqueous Solution Induced by a Chemical Stimulus. Inorganic Chemistry, 2012, 51 (1), pp.31-33. ⟨10.1021/ic202268e⟩. ⟨hal-01121311⟩