Cryptophanes

Thierry Brotin (1) , Jean-Pierre Dutasta (1)

1 LC - Laboratoire de Chimie - UMR5182

Cryptophanes are organic molecular receptors known for their complexation properties toward neutral and cationic species in organic or aqueous media. Small halogenomethanes and alkanes, monoatomic xenon, as well as ammonium and metal cations are reversibly entrapped into the molecular cavity of the cryptophanes. Different synthetic routes have been developed to construct cryptophanes with peculiar functionalities that are key compounds for biological applications. Throughout this contribution, a brief survey of their structures and complexation properties are reviewed, that enlighten the possible applications of these organic hosts in molecular recognition, chiral recognition, and biosensing.

Mots clés: Cation complexation; Chiral hosts; Chiral recognition; Cryptophane; Complexation; Host–guest chemistry; Molecular cages; Molecular containers; Molecular recognition; Organic synthesis; Organic chemistry; Supramolecular chemistry; Xenon complexation; van der Waals complexes; Substrate encapsulation

Domaines: Chimie théorique et/ou physique

Thierry Brotin, Jean-Pierre Dutasta. Cryptophanes. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2013, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, pp.1. ⟨10.1016/B978-0-12-409547-2.05605-5⟩. ⟨hal-01117268⟩