Azole-resistant Aspergillus fumigatus isolate with the TR34/L98H mutation in both a fungicide-sprayed field and the lung of a hematopoietic stem cell transplant recipient with invasive aspergillosis.

Abstract : A French farmer developed invasive aspergillosis with azole-resistant Aspergillus fumigatus with the TR34/L98H mutation following a hematopoietic stem cell transplantation. He had worked in fungicide-sprayed fields where a non-genetically related A. fumigatus TR34/L98H isolate was collected. If azole resistance detection increases, voriconazole as first-line therapy might be questioned in agricultural areas.
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https://hal.archives-ouvertes.fr/hal-01063888
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Submitted on : Monday, September 15, 2014 - 9:15:21 AM
Last modification on : Monday, February 25, 2019 - 12:22:06 PM

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Steffi Rocchi, Etienne Daguindau, Frédéric Grenouillet, Eric Deconinck, Anne-Pauline Bellanger, et al.. Azole-resistant Aspergillus fumigatus isolate with the TR34/L98H mutation in both a fungicide-sprayed field and the lung of a hematopoietic stem cell transplant recipient with invasive aspergillosis.. Journal of Clinical Microbiology, American Society for Microbiology, 2014, 52 (5), pp.1724-6. ⟨10.1128/JCM.03182-13⟩. ⟨hal-01063888⟩

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