Cells driven by computers: long-term model predictive control of gene expression in yeast (keynote talk)

Gregory Batt (1)

1 Lifeware - Computational systems biology and optimization

Real-time control has been recently applied to drive actual intracellular processes with unprecedented accuracy. Here we introduce the motivations for the development of these approaches and then present a platform for the real-time control of gene expression in yeast cells. We conclude by surveying related works and discussing possible future directions.

Mots clés: synthetic biology; gene expression; computational biology; systems biology; yeast

Domaines: Optimisation et contrôle [math.OC]; Bio-Informatique, Biologie Systémique [q-bio.QM]; Bio-informatique [q-bio.QM]

Gregory Batt. Cells driven by computers: long-term model predictive control of gene expression in yeast (keynote talk). Proceedings of the 17th international conference on Hybrid Systems: Computation and Control, HSCC'14, Martin Fráänzle, John Lygeros, Apr 2014, Berlin, Germany. pp.2, ⟨10.1145/2562059.2562144⟩. ⟨hal-01104055⟩