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Super-resolution Microscopy Approaches for Live Cell Imaging

Antoine Godin 1 Brahim Lounis 1 Laurent Cognet 1, *
* Corresponding author
1 lp2n-04,lp2n-12
LP2N - Laboratoire Photonique, Numérique et Nanosciences
Abstract : By delivering optical images with spatial resolutions below the diffraction limit several super-resolution fluorescence microscopy techniques opened new opportunities to study biological structures with details approaching molecular structure sizes. They have now become methods of choice for imaging proteins and their nano-scale dynamic organizations in live cells. In this mini-review, we describe and compare the main far-field super-resolution approaches that allow studying endogenous or overexpressed proteins in live cells.
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Submitted on : Thursday, November 6, 2014 - 9:59:34 AM
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Antoine Godin, Brahim Lounis, Laurent Cognet. Super-resolution Microscopy Approaches for Live Cell Imaging. Biophysical Journal, Biophysical Society, 2014, 107, pp.1777 - 1784. ⟨10.1016/j.bpj.2014.08.028⟩. ⟨hal-01080729⟩



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