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Article Dans Une Revue Journal of Biomechanics Année : 2014

In vitro Analysis of Localized Aneurysm Rupture

Aaron Romo
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Pierre Badel
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Ambroise Duprey
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Jean-Pierre Favre
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Stéphane Avril

Résumé

In this study, bulge inflation tests were used to characterize the failure response of 15 layers of human ascending thoracic aortic aneurysms (ATAA). Full field displacement data were collected during each of the mechanical tests using a digital image stereo-correlation (DIS-C) system. Using the collected displacement data, the local stress fields at burst were derived and the thickness evolution was estimated during the inflation tests. It was shown that rupture of the ATAA does not systematically occur at the location of maximum stress, but in a weakened zone of the tissue where the measured fields show strain localization and localized thinning of the wall. Our results are the first to show the existence of weakened zones in the aneurysmal tissue when rupture is imminent. An understanding these local rupture mechanics is necessary to improve clinical assessments of aneurysm rupture risk. Further studies must be performed to determine if these weakened zones can be detected in vivo using non-invasive techniques.
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Dates et versions

hal-01025664 , version 1 (18-07-2014)

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  • HAL Id : hal-01025664 , version 1

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Aaron Romo, Pierre Badel, Ambroise Duprey, Jean-Pierre Favre, Stéphane Avril. In vitro Analysis of Localized Aneurysm Rupture. Journal of Biomechanics, 2014, 47 (3), pp.607-616. ⟨hal-01025664⟩
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