Modeling the fate of dietary phosphorus in the digestive tract of growing pigs

M.P. M.P. Létourneau-Montminy , Agnès Narcy (1) , Philippe Lescoat (1) , M. M. Magnin , J.F. J. Bernier , Daniel Sauvant (2) , Catherine C. Jondreville (3) , C. C. Pomar

1 URA - Unité de Recherches Avicoles
2 MoSAR - Modélisation Systémique Appliquée aux Ruminants
3 URAFPA - Unité de Recherches Animal et Fonctionnalités des Produits Animaux

Environmental effects of the excess of P from manure and the soaring price of phosphates are major issues in pig production. To optimize P utilization, it is crucial to improve our capacity to predict the amount of P absorbed, while taking into account the main factors of variation. Mathematical modeling can represent the complexity of the processes and interactions in determining the digestive utilization of phosphorus in growing pigs. This paper describes and evaluates a model developed to simulate the fate of the dietary forms of P in the digestive tract of growing pigs, with particular emphasis on the impact of dietary Ca and exogenous phytase on P digestive utilization. The model consists of 3 compartments associated with specific anatomical sections: stomach, proximal small intestine, and distal small intestine. The main metabolic processes occurring in these sections are, respectively, P solubilization/insolubilization and phytate P hydrolysis, and P absorption and P insolubilization. Model parameters governing these flows were derived from in vitro and in vivo literature data. The sensitivity analysis revealed that the model was stable within a large range of model parameter values (± 1.5 SD). The model was able to predict the efficacy of Aspergillus niger microbial phytase in accordance with literature values, as well as the lower efficacy of plant phytase compared to microbial phytase. The prediction capabilities of the model were assessed by comparing actual and simulated P and Ca apparent total tract digestibility (ATTD) based on published pig data not used for model development. Prediction of P digestibility across 66 experiments and 281 observations was adequate [P ATTD observed = 0.24 (SE, 0.943 + 0.98 (SE, 0.0196) × P ATTD predicted; R2, 0.90; disturbance error (ED), 3.1%], whereas prediction of Ca digestibility across 47 experiments and 193 observations was less accurate (Ca ATTD observed = 11.1 + 0.75 × Ca ATTD predicted; R2, 0.78; ED, 71.3%). The lack of agreement between experimental and simulated Ca digestibility was found. This model is, therefore, useful in evaluating P digestibility for different feedstuffs and feeding strategies. It can also be used to provide insight for improving dietary P utilization, especially from plant sources, by quantifying the impact of the mean sources of variation affecting P utilization.

Mots clés: pig; phytase; digestion; phosphorus; mathematical model; calcium

Domaines: Science des productions animales

M.P. M.P. Létourneau-Montminy, Agnès Narcy, Philippe Lescoat, M. M. Magnin, J.F. J. Bernier, et al.. Modeling the fate of dietary phosphorus in the digestive tract of growing pigs. Journal of Animal Science, 2011, 89 (11), pp.3596-3611. ⟨10.2527/jas.2010-3397⟩. ⟨hal-01000188⟩