Multi-residue analysis of emerging pollutants in sediment using QuEChERS-based extraction followed by LC-MS/MS analysis.

Abstract : Emerging contaminants are suspected to cause adverse effects in humans and wildlife. Aquatic ecosystems are continuously contaminated by agricultural and industrial sources. To establish a causality relationship between the occurrence of contaminants in the environment and disease, experiments including all environmental matrices must be performed. Consequently, the current analytical tools must be improved. A new multi-residue method for analysing 15 emerging pollutants in sediments based on the Quick, Easy, Cheap, Effective, Rugged and Safe approach is reported. The development of such a multirisque, inter-family method for sediment including pharmaceuticals, pesticides, personal care products and plasticizers is reported for the first time. The procedure involves salting-out liquid-liquid extraction using acetonitrile and clean-up with dispersive solid phase extraction, followed by liquid chromatography coupled with tandem mass spectrometry. The validated analytical procedure exhibited recoveries between 40 and 98 % for every target compound. This methodology facilitated the determination of pollutant contents at nanogram-per-gram concentrations.
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Submitted on : Wednesday, March 5, 2014 - 4:01:27 PM
Last modification on : Thursday, February 8, 2018 - 11:10:19 AM

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Alexandra Berlioz-Barbier, Antoine Vauchez, Laure Wiest, Robert Baudot, Emmanuelle Vulliet, et al.. Multi-residue analysis of emerging pollutants in sediment using QuEChERS-based extraction followed by LC-MS/MS analysis.. Analytical and Bioanalytical Chemistry, Springer Verlag, 2014, 406 (4), pp.1259-1266. ⟨10.1007/s00216-013-7450-8⟩. ⟨hal-00955924⟩

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