Fluorescent Vesicles Consisting of Galactose-based Amphiphilic Copolymers with a pi-Conjugated Sequence Self-assembled in Water

Karim Aissou (1, 2) , Andre Pfaff (3, 4) , Cristiano Giacomelli (5) , Christophe Travelet (6) , Axel H. E. Müller (3, 4) , Redouane Borsali (6)

1 LCPO - Laboratoire de Chimie des Polymères Organiques
2 Team 4 LCPO : Polymer Materials for Electronic, Energy, Information and Communication Technologies
3 Universität Bayreuth
4 Bayreuther Zentrum Kolloide & Grenzflachen
5 Univ Fed Santa Maria, Dept Quim
6 CERMAV - Centre de Recherches sur les Macromolécules Végétales

Fluorescent vesicles considered as a mimic of natural primitive cells are prepared from poly(3-hexylthiophene)-block-poly(3-O-methacryloyl-D-galactopyranose) P3HT-b-PMAGP copolymers. The unique characteristic of such vesicular nanostructures is their architecture, which comprises a hydrophobic pi-conjugated P3HT wall stabilized by a hydrophilic PMAGP interface featuring glucose units. The results of this work offer a very efficient and straightforward method for engineering well-controlled fluorescent nanoparticles (without the addition of dyes), which provide an excellent support to the study of carbohydrate-protein interactions.

Mots clés: block copolymers; fluorescence; nanoparticles; self-assembly; vesicles

Domaines: Polymères

Karim Aissou, Andre Pfaff, Cristiano Giacomelli, Christophe Travelet, Axel H. E. Müller, et al.. Fluorescent Vesicles Consisting of Galactose-based Amphiphilic Copolymers with a pi-Conjugated Sequence Self-assembled in Water. Macromolecular Rapid Communications, 2011, 32 (12), pp.912-916. ⟨10.1002/marc.201100054⟩. ⟨hal-00951675⟩