Endoluminal MRI coils for mice rectal wall assessment
Résumé
Background and purpose: MRI is well suited to investigate human body and provide a good spatial resolution and contrast for the characterization and staging of lesions (1). Nevertheless, rectal wall assessment requires an even higher spatial resolution for visualizing different wall layers (2) (0.1-0.5 mm) in detail still within a limited acquisition time. Endoluminal coil is drastically increasing local signal-to-noise ratio (SNR) compared to external coils. The purpose of the research project is to assess mice rectal wall for lesion characterization and staging (colorectal cancer and inflammatory bowel disease) using MRI combined with confocal endomicroscopy and conventional endoscopy (4). In this abstract, endoluminal coils were built and assessed compared to volume coil to explore rectal region in mice.