Luminogenic "Clickable" Lanthanide Complexes for Protein Labeling.

Nicolas Candelon (1) , Niculina D. Hădade , Mihaela Matache , Jean-Louis Canet (1) , Federico Cisnetti (1) , Daniel P. Funeriu , Lionel Nauton (1) , Arnaud Gautier (1)

1 ICCF - Institut de Chimie de Clermont-Ferrand

Development of lanthanide-based luminescent "switch-on" systems via azide-alkyne [3+2] cycloaddition is described. We used these for non-specific protein labeling and as tags for specific and selective activity-based protein labeling.

Nicolas Candelon, Niculina D. Hădade, Mihaela Matache, Jean-Louis Canet, Federico Cisnetti, et al.. Luminogenic "Clickable" Lanthanide Complexes for Protein Labeling.. Chemical Communications, 2013, 49, pp.9206-9208. ⟨hal-00950489⟩