Love wave sensor based on thin film molecularly imprinted polymer : MIP layer morphology and nucleosides analogs detection

Nima Omar-Aouled 1 Hamida Hallil 1 Bernard Plano 1 Raphaël Delépée 2 Luigi A. Agrofoglio 2 Corinne Dejous 1 Dominique Rebière 1
1 IMS - Laboratoire de l'intégration, du matériau au système
2 ICOA - Institut de Chimie Organique et Analytique
Abstract : SH-SAW sensing system combined with molecularly imprinted polymer (MIP) is introduced. The overall aim of this work is to develop and validate a quantitative, non-invasive diagnosis tool for specific detection of colon cancer biomarkers. This paper exhibits the validation of a MIP thin film coating process, allowing a high sensitivity of the resulting sensor. Morphology and print effect of the MIP film (sensitive layer) is the key of the sensor sensitivity to target biomarkers. Thereby, the real time detection measurement of the coated sensor under ethanol such as deep characterization of the film is presented. The rise of the MIP film thickness and detection of biomarkers analogs leads to a change of the sensors' responses to vapors. For example, 2126 ppm of ethanol generates frequency shifts of -1.4/-2.5kHz with MIP 200nm/600nm thickness. For the same ethanol concentration frequency shifts of -0.5/-1.3/-0.8 kHz, MIP/MIP after extraction/MIP after rebinding were observed respectively.
Keywords : SH-SAW wave Polymer MIP Thin film Sensor
Document type :
Conference papers
Complete list of metadatas
https://hal.archives-ouvertes.fr/hal-00938274
Contributor : Corinne Dejous <>
Submitted on : Wednesday, January 29, 2014 - 11:45:01 AM
Last modification on : Thursday, February 7, 2019 - 12:10:02 PM

Identifiers

  • HAL Id : hal-00938274, version 1

Collections

UNIV-ORLEANS | ICOA | IMS-BORDEAUX | IMS-BORDEAUX-FUSION

Citation

Nima Omar-Aouled, Hamida Hallil, Bernard Plano, Raphaël Delépée, Luigi A. Agrofoglio, et al.. Love wave sensor based on thin film molecularly imprinted polymer : MIP layer morphology and nucleosides analogs detection. IEEE SENSORS 2013, Nov 2013, Baltimore, United States. ID 7218, 4p. ⟨hal-00938274⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

154

Contact

support.ccsd.cnrs.fr
hal.support@ccsd.cnrs.fr
Logo CCSD