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Journal articles

Isolation and characteristics of matrix vesicles

Abstract : Mineralizing matrix vesicles (MVs) are extracellular organelles produced by chondrocytes, osteoblasts, and odontoblasts under physiological conditions and by vascular smooth muscle cells under pathological conditions. MVs are involved in the early stage of mineralization allowing calcium and phosphate to accumulate, and therefore providing an optimal environment facilitating hydroxyapatite formation. Here, we describe the isolation of MVs from osteoblasts and chondrocytes and present their main characteristics.
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Contributor : Frédérique Depierre <>
Submitted on : Thursday, December 12, 2013 - 5:12:41 PM
Last modification on : Friday, June 25, 2021 - 7:38:02 PM


  • HAL Id : hal-00917990, version 1


René Buchet, Slawomir Pikula, David Magne, Saïda Mebarek. Isolation and characteristics of matrix vesicles. Methods in Molecular Biology, Humana Press/Springer Imprint, 2013, 1053, pp.115-124. ⟨hal-00917990⟩



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