Quenched fluorescence and enhanced resonant light scattering in molecular plasmonic assemblies

Abstract : Isolated gold nanoparticles in liquid suspension can effectively quench the fluorescence of molecules that are nearby (< 10 nm), e.g. fluorophores attached to the particles via molecular linkers. Using fluorescence correlation spectroscopy, which analyses the fluorescence from individual objects in a small probe volume, we have been able to demonstrate unambiguously the quenching of ligated chromophores, and to identify spontaneously desorbed ligands that display fluorescence [1,2]. Enhancement of molecular spectroscopic responses may occur at 'hot spots' in aggregates of plasmonic nanoparticles. Moreover, such aggregates display an intense, and specific, resonant light scattering, which in itself provides a useful signal for optical detection at low concentrations in small volumes [3]. We are currently investigating the reversible aggregation of various functionalised gold nanoparticles, using microfluidic systems [4] as a platform for precise control of the aggregation as well as for the development of new (molecular plasmonic) biosensing schemes. Funding by ERANet-NanoSci (MOLIMEN) and ANR (JCJC 2010, COMONSENS) is gratefully acknowledged. [1] M. Loumaigne, R. Praho, D. Nutarelli, M. H. V Werts and A. Débarre, Phys. Chem. Chem. Phys. 12 (2010) 11004-11014 [2] J. R. G. Navarro, M. Plugge, M. Loumaigne, A. Sanchez-Gonzalez, B. Mennucci, A. Débarre, A. M. Brouwer, M. H. V Werts, Photochem. Photobiol. Sci. 9 (2010) 1042-1054 [3] J. R. G. Navarro and M. H. V Werts. Analyst 138 (2013) 583-592 [4] M. H. V. Werts, V. Raimbault, R. Texier-Picard, R. Poizat, O. Français, L. Griscom and J. R. G. Navarro, Lab on a Chip 12 (2012) 808-820
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https://hal.archives-ouvertes.fr/hal-00877127
Contributor : Martinus H. V. Werts <>
Submitted on : Saturday, October 26, 2013 - 12:31:02 PM
Last modification on : Thursday, July 4, 2019 - 6:28:09 AM

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  • HAL Id : hal-00877127, version 1

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Martinus H. V. Werts, Matthieu Loumaigne, Julien R. G. Navarro, A. Débarre, Laurent Griscom, et al.. Quenched fluorescence and enhanced resonant light scattering in molecular plasmonic assemblies. Molecular Plasmonics 2013, May 2013, Jena, Germany. ⟨hal-00877127⟩

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