Real time optical method for localization of inclusions embedded in turbid media

Anabela da Silva (1, 2) , Nadia Djaker (3, 2) , Nicolas Ducros (2, 4) , Jean-Marc Dinten (2) , Philppe Rizo (2)

1 DiMABio - DiMABio
2 LISA - Laboratoire Imagerie et Systèmes d'Acquisition
3 MOSAIC - MOSAIC
4 CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé

A simple and fast time-domain method for localizing inclusions, fluorescent optical probes or absorbers, is presented. The method offers new possibilities for situations where complete tomographic measurements are not permitted by the examined object, for example in endoscopic examination of the human prostate or the oesophagus. Feasibility has been envisioned with a phantom study conducted on a point-like fluorochrome embedded in a diffusing medium mimicking the optical properties of biological tissues.

Mots clés: laser-induced; Fluorescence; Turbid media; Time-resolved imaging; Medical and biological imaging; Photon migration; Light propagation in tissues; laser-induced

Domaines: Imagerie médicale; Optique [physics.optics]; Optique / photonique; Traitement du signal et de l'image [eess.SP]

Anabela da Silva, Nadia Djaker, Nicolas Ducros, Jean-Marc Dinten, Philppe Rizo. Real time optical method for localization of inclusions embedded in turbid media. Optics Express, 2010, 18 (8), pp.7753--7762. ⟨10.1364/OE.18.007753⟩. ⟨hal-00875195⟩