A. P. Kozikowski, The isoxazoline route to the molecules of nature, Accounts of Chemical Research, vol.17, issue.12, pp.410-416, 1984.
DOI : 10.1021/ar00108a001

T. Nakajima, D. Yamashita, K. Suzuki, A. Nakazaki, T. Suzuki et al., Different Modes of Cyclization in Zoanthamine Alkaloid System, Bisaminal versus Spiroketal Formation, Organic Letters, vol.13, issue.12, pp.2980-2983, 2011.
DOI : 10.1021/ol200486c

J. E. Aho, P. M. Pihko, and T. K. Rissa, Nonanomeric Spiroketals in Natural Products:?? Structures, Sources, and Synthetic Strategies, Chemical Reviews, vol.105, issue.12, pp.4406-4440, 2005.
DOI : 10.1021/cr050559n

S. Kotha, M. K. Dipak, and S. M. Mobin, Serendipitous and acid catalyzed synthesis of spirolactones, Tetrahedron, vol.67, issue.25, pp.4616-4619, 2011.
DOI : 10.1016/j.tet.2011.04.073

M. S. Chande, R. S. Verma, P. A. Barve, R. R. Khanwelkar, R. B. Vaidya et al., Facile synthesis of active antitubercular, cytotoxic and antibacterial agents: a Michael addition approach, European Journal of Medicinal Chemistry, vol.40, issue.11, pp.1143-1148, 2005.
DOI : 10.1016/j.ejmech.2005.06.004

L. I. Palmer and J. Read-de-alaniz, Direct and Highly Diastereoselective Synthesis of Azaspirocycles by a Dysprosium(III) Triflate Catalyzed Aza-Piancatelli Rearrangement, Angewandte Chemie International Edition, vol.91, issue.31, pp.7167-7170, 2011.
DOI : 10.1002/anie.201102102

R. Bandichhor, A. N. Lowell, and M. C. Kozlowski, Alternative Spiroketalization Methods toward Purpuromycin: A Hemiketal Conjugate Addition Strategy and Use of an Electron-Rich Isocoumarin Precursor, The Journal of Organic Chemistry, vol.76, issue.16, pp.6475-6487, 2011.
DOI : 10.1021/jo200398v

J. J. Omolo, M. M. Johnson, S. F. Van-vuuren, and C. B. De-koning, The synthesis of xanthones, xanthenediones, and spirobenzofurans: Their antibacterial and antifungal activity, Bioorganic & Medicinal Chemistry Letters, vol.21, issue.23, pp.7085-7088, 2011.
DOI : 10.1016/j.bmcl.2011.09.088

B. Lv, Y. Feng, J. Dong, M. Xu, B. Xu et al., Conformationally Constrained Spiro C-Arylglucosides as Potent and Selective Renal Sodium-Dependent Glucose Co-transporter???2 (SGLT2) Inhibitors, ChemMedChem, vol.27, issue.6, pp.827-831, 2010.
DOI : 10.1002/cmdc.201000051

C. Fytas, G. Zoidis, N. Tzoutzas, M. C. Taylor, G. Fytas et al., Novel Lipophilic Acetohydroxamic Acid Derivatives Based on Conformationally Constrained Spiro Carbocyclic 2,6-Diketopiperazine Scaffolds with Potent Trypanocidal Activity, Journal of Medicinal Chemistry, vol.54, issue.14, pp.5250-5254, 2011.
DOI : 10.1021/jm200217m

Z. Z. Brown, C. E. Schafmeister, A. M. Kendhale, R. Gonnade, P. R. Rajamohanan et al., Synthesis of Hexa- and Pentasubstituted Diketopiperazines from Sterically Hindered Amino Acids, Organic Letters, vol.12, issue.7, pp.1436-1439, 2008.
DOI : 10.1021/ol100048g

Z. Z. Brown, J. Alleva, and C. E. Schafmeister, Solid-phase synthesis of functionalized bis-peptides, Biopolymers, vol.117, issue.5, pp.578-585, 2011.
DOI : 10.1002/bip.21591

C. E. Schafmeister, L. G. Belasco, and P. H. Brown, Observation of Contraction and Expansion in a Bis(peptide)-Based Mechanical Molecular Actuator, Chemistry - A European Journal, vol.320, issue.21, pp.6406-6412, 2008.
DOI : 10.1002/chem.200701942

M. J. Genin, W. H. Ojala, W. B. Gleason, and R. L. Johnson, Synthesis and crystal structure of a peptidomimetic containing the (R)-4.4-spiro lactam type-II .beta.-turn mimic, The Journal of Organic Chemistry, vol.58, issue.8, pp.2334-2337, 1993.
DOI : 10.1021/jo00060a062

M. G. Hinds, J. H. Welsh, D. M. Brennand, J. Fisher, M. J. Glennie et al., Synthesis, conformational properties, and antibody recognition of peptides containing .beta.-turn mimetics based on .alpha.-alkylproline derivatives, Journal of Medicinal Chemistry, vol.34, issue.6, pp.1777-1789, 1991.
DOI : 10.1021/jm00110a005

M. J. Genin, R. K. Mishra, and R. L. Johnson, Dopamine receptor modulation by a highly rigid spiro bicyclic peptidomimetic of Pro-Leu-Gly-NH2, Journal of Medicinal Chemistry, vol.36, issue.22, pp.3481-3483, 1993.
DOI : 10.1021/jm00074a032

D. J. Witter, S. J. Famiglietti, J. C. Cambier, and A. L. Castelhano, Design and synthesis of SH3 domain binding ligands: Modifications of the consensus sequence XPpXP, Bioorganic & Medicinal Chemistry Letters, vol.8, issue.22, pp.3137-3142, 1998.
DOI : 10.1016/S0960-894X(98)00577-0

I. Parrot, P. C. Huang, and C. Khosla, Circular Dichroism and Nuclear Magnetic Resonance Spectroscopic Analysis of Immunogenic Gluten Peptides and Their Analogs, Journal of Biological Chemistry, vol.277, issue.47, pp.45572-45578, 2002.
DOI : 10.1074/jbc.M207606200

M. P. Williamson, The structure and function of proline-rich regions in proteins, Biochemical Journal, vol.297, issue.2, pp.249-260, 1994.
DOI : 10.1042/bj2970249

D. C. Dalgarno, M. C. Botfield, and R. J. Rickles, SH3 domains and drug design: Ligands, structure, and biological function, Biopolymers, vol.25, issue.5, pp.383-400, 1997.
DOI : 10.1002/(SICI)1097-0282(1997)43:5<383::AID-BIP4>3.0.CO;2-R

Z. Shi, K. Chen, Z. Liu, and N. R. Kallenbach, Conformation of the Backbone in Unfolded Proteins, Chemical Reviews, vol.106, issue.5, pp.1877-1897, 2006.
DOI : 10.1021/cr040433a

B. Bochicchio and A. M. Tamburro, Polyproline II structure in proteins: Identification by chiroptical spectroscopies, stability, and functions, Chirality, vol.364, issue.10, pp.782-792, 2002.
DOI : 10.1002/chir.10153

G. Siligardi and A. F. Drake, The importance of extended conformations and, in particular, the PII conformation for the molecular recognition of peptides, Biopolymers, vol.262, issue.4, pp.281-292, 1995.
DOI : 10.1002/bip.360370406

M. Kümin, L. Sonntag, and H. Wennemers, Azidoproline Containing Helices:?? Stabilization of the Polyproline II Structure by a Functionalizable Group, Journal of the American Chemical Society, vol.129, issue.3, pp.466-467, 2007.
DOI : 10.1021/ja067148o

F. Bernardi, M. Garavelli, M. Scatizzi, C. Tomasini, V. Trigari et al., Pseudopeptide Foldamers: The Homo-Oligomers of Pyroglutamic Acid, Chemistry - A European Journal, vol.8, issue.11, pp.2516-2525, 2002.
DOI : 10.1002/1521-3765(20020603)8:11<2516::AID-CHEM2516>3.0.CO;2-K

R. Zhang, F. Brownewell, and J. S. Madalengoitia, -proline Type II Peptide Mimics, Journal of the American Chemical Society, vol.120, issue.16, pp.3894-3902, 1998.
DOI : 10.1021/ja972494e
URL : https://hal.archives-ouvertes.fr/hal-01258459

A. Mamai, R. Zhang, A. Natarajan, and J. S. Madalengoitia, -proline Type II Peptide Mimics Based on the 3-Azabicyclo[3.1.0]hexane System, The Journal of Organic Chemistry, vol.66, issue.2, pp.455-460, 2001.
DOI : 10.1021/jo001201o
URL : https://hal.archives-ouvertes.fr/hal-01299974

S. Flemer, A. Wurthmann, A. Mamai, and J. S. Madalengoitia, -proline-Type II Peptide Mimic Scaffolds and Peptide Scaffolds Through Guanidinylation, The Journal of Organic Chemistry, vol.73, issue.19, pp.7593-7602, 2008.
DOI : 10.1021/jo8012258

B. Raghavan, K. J. Skoblenick, S. Bhagwanth, N. Argintaru, R. K. Mishra et al., Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II ??-Turn Conformation, Journal of Medicinal Chemistry, vol.52, issue.7, pp.2043-2051, 2009.
DOI : 10.1021/jm801575w

R. V. Somu and R. L. Johnson, Synthesis of Pipecolic Acid-Based Spiro Bicyclic Lactam Scaffolds as ??-Turn Mimics, The Journal of Organic Chemistry, vol.70, issue.15, pp.5954-5963, 2005.
DOI : 10.1021/jo050529k

P. Tremmel and A. Geyer, An Oligomeric Ser-Pro Dipeptide Mimetic Assuming the Polyproline II Helix Conformation, Journal of the American Chemical Society, vol.124, issue.29, pp.8548-8549, 2002.
DOI : 10.1021/ja026098u

D. Farran, I. Parrot, J. Martinez, and G. Dewynter, Transannular Rearrangement of Activated Lactams: Stereoselective Synthesis of Substituted Pyrrolidine-2,4-diones from Diketopiperazines, Angewandte Chemie International Edition, vol.46, issue.39, pp.7488-7490, 2007.
DOI : 10.1002/anie.200702132
URL : https://hal.archives-ouvertes.fr/hal-00359100

D. Farran, I. Parrot, L. Toupet, J. Martinez, and G. Dewynter, Transannular rearrangement of activated 2,5-diketopiperazines: a key route to original scaffolds, Organic & Biomolecular Chemistry, vol.117, issue.21, pp.3989-3996, 2008.
DOI : 10.1039/b810352f
URL : https://hal.archives-ouvertes.fr/hal-00359095

T. Coursindel, A. Restouin, G. Dewynter, J. Martinez, Y. Collette et al., Stereoselective ring contraction of 2,5-diketopiperazines: An innovative approach to the synthesis of promising bioactive 5-membered scaffolds, Bioorganic Chemistry, vol.38, issue.5, pp.210-217, 2010.
DOI : 10.1016/j.bioorg.2010.05.002
URL : https://hal.archives-ouvertes.fr/hal-00599350

S. C. Gatling and J. E. Jackson, Reactivity Control via Dihydrogen Bonding:?? Diastereoselection in Borohydride Reductions of ??-Hydroxyketones, Journal of the American Chemical Society, vol.121, issue.37, pp.8655-8656, 1999.
DOI : 10.1021/ja991784n

N. Srinivasan, A. Yurek-george, and A. Ganesan, Rapid deprotection of N-Boc amines by TFA combined with freebase generation using basic ion-exchange resins, Molecular Diversity, vol.1, issue.4, pp.291-293, 2005.
DOI : 10.1007/s11030-005-4386-8

P. Majer and R. S. Randad, A Safe and Efficient Method for Preparation of N,N'-Unsymmetrically Disubstituted Ureas Utilizing Triphosgene, The Journal of Organic Chemistry, vol.59, issue.7, pp.1937-1938, 1994.
DOI : 10.1021/jo00086a061

F. Rabanal, M. D. Ludevid, M. Pons, and E. Giralt, CD of proline-rich polypeptides: Application to the study of the repetitive domain of maize glutelin-2, Biopolymers, vol.96, issue.7, pp.1019-1028, 1993.
DOI : 10.1002/bip.360330704

G. D. Fasman, Circular dichroism and the conformational analysis of biomolecules, 1996.
DOI : 10.1007/978-1-4757-2508-7

M. L. Tiffany and S. Krimm, Circular dichroism of poly-L-proline in an unordered conformation, Biopolymers, vol.58, issue.12, pp.1767-1770, 1968.
DOI : 10.1002/bip.1968.360061212

C. Lee, K. Saksela, U. A. Mirza, B. T. Chait, and J. Kuriyan, Crystal Structure of the Conserved Core of HIV-1 Nef Complexed with a Src Family SH3 Domain, Cell, vol.85, issue.6, pp.931-942, 1996.
DOI : 10.1016/S0092-8674(00)81276-3

S. Kwon, A. Jeon, S. H. Yoo, I. S. Chung, and H. Lee, Unprecedented Molecular Architectures by the Controlled Self-Assembly of a ??-Peptide Foldamer, Angewandte Chemie International Edition, vol.117, issue.44, pp.8232-8236, 2010.
DOI : 10.1002/anie.201003302