Simulation of Gene Regulatory Networks

Bernard Ycart (1) , Frédéric Pont (2) , Jean-Jacques Fournié (2)

1 IPS - Inférence Processus Stochastiques
2 CRCT - Centre de Recherches en Cancérologie de Toulouse

This limited review is intended as an introduction to the fast growing subject of mathematical modelling of cell metabolism and its biochemical pathways, and more precisely on pathways linked to apoptosis of cancerous cells. Some basic mathematical models of chemical kinetics, with emphasis on stochastic models, are presented.

Mots clés: biochemical pathways; kinetics; master equation; diffusion processes; simulation

Domaines: Probabilités [math.PR]

Bernard Ycart, Frédéric Pont, Jean-Jacques Fournié. Simulation of Gene Regulatory Networks. [Research Report] LJK. 2011. ⟨hal-00869111⟩