International network of cancer genome projects.

Thomas J. Hudson , Warwick Anderson , Axel Artez , Anna D. Barker , Cindy Bell , Rosa R. Bernabé , M. K. Bhan , Fabien Calvo , Iiro Eerola , Daniela S. Gerhard , Alan Guttmacher , Mark Guyer , Fiona M. Hemsley , Jennifer L. Jennings , David Kerr , Peter Klatt , Patrik Kolar , Jun Kusuda , David P. Lane , Frank Laplace , Youyong Lu , Gerd Nettekoven , Brad Ozenberger , Jane Peterson , T.S. Rao , Jacques Remacle , Alan J. Schafer , Tatsuhiro Shibata , Michael R. Stratton , Joseph G Vockley , Koichi Watanabe , Huanming Yang , Matthew M. F. Yuen , Bartha Maria Bm Knoppers , Martin Bobrow , Anne Cambon-Thomsen , Lynn G Dressler , Stephanie O. M. Dyke , Yann Joly , Kazuto Kato , Karen L. Kennedy , Pilar Nicolás , Michael J. Parker , Emmanuelle Rial-Sebbag , Carlos M Romeo-Casabona , Kenna M. Shaw , Susan Wallace , Georgia L Wiesner , Nikolajs Zeps , Peter Lichter , Andrew V Biankin , Christian Chabannon , Lynda Chin , Bruno Clément (1) , Enrique de Alava , Françoise Degos , Martin L. Ferguson , Peter Geary , D. Neil Hayes , Amber L. Johns , Arek Kasprzyk , Hidewaki Nakagawa , Robert Penny , Miguel A. Piris , Rajiv Sarin , Aldo Scarpa , Marc van de Vijver , Hiroyuki Aburatani , Mónica Bayés , David D L Bowtell , Peter J. Campbell , Xavier Estivill , P Andrew Futreal , Daniela S Gerhard , Sean M Grimmond , Ivo G Gut , Martin Hirst , Carlos López-Otín , Partha Majumder , Marco Marra , John D Mcpherson , Zemin Ning , Xose S Puente , Yijun Ruan , Hendrik G Stunnenberg , Harold Swerdlow , Victor E Velculescu , Richard K. Wilson , Hong H. Xue , Liu Yang , Paul T Spellman , Gary D. Bader , Paul C Boutros , Paul Flicek , Gad Getz , Roderic Guigo , Guangwu Guo , David Haussler , Simon Heath , Tim J. Hubbard , Tao Jiang , Steven M. Jones , Qibin Li , Nuria López-Bigas , Ruibang Luo , Lakshmi Muthuswamy , B F Francis Ouellette , John V. Pearson , Victor Quesada , Benjamin J. Raphael , Chris Sander , Terence P Speed , Lincoln D. Stein , Joshua M. Stuart , Jon W Teague , Yasushi Totoki , Tatsuhiko Tsunoda , Alfonso Valencia , David A. Wheeler , Honglong Wu , Shancen Zhao , Guangyu Zhou , Mark Lathrop , Paul T. Spellman , Gilles Thomas , Teruhiko Yoshida , Myles Axton , P. Andrew Futreal , Chris Gunter , Linda J. Miller , Junjun Zhang , Syed A Haider , Jianxin Wang , Christina K Yung , Anthony Cross , Yong Liang , Saravanamuttu Gnaneshan , Jonathan Guberman , Jack Hsu , Don R. C. Chalmers , Karl W Hasel , Terry S. H. Kaan , Bartha M Knoppers , William W Lowrance , Tohru Masui , Laura Lyman Rodriguez , Catherine Vergely , Sean M. Grimmond , Andrew V. Biankin , David D. L. Bowtell , Nicole Cloonan , Anna de Fazio , James R. Eshleman , Dariush Etemadmoghadam , Brooke A. Gardiner , James G Kench , Robert L. Sutherland , Margaret A Tempero , Nicola J Waddell , Peter J. Wilson , Steve Gallinger , Ming-Sound Tsao , Patricia A. Shaw , Gloria M. Petersen , Debabrata Mukhopadhyay , Ronald A. de Pinho , Sarah Thayer , Kamran Shazand , Timothy Beck , Michelle Sam , Lee Timms , Vanessa Ballin , Jiafu Ji , Xiuqing Zhang , Feng Chen , Xueda Hu , Qi Yang , Geng Tian , Lianhai Zhang , Xiaofang Xing , Xianghong Li , Zhenggang Zhu , Yingyan Yu , Jun Yu , Jörg Tost , Paul Brennan , Ivana Holcatova , David Zaridze , Alvis Brazma , Lars Egevad , Egor Prokhortchouk , Rosamonde Elizabeth Banks , Mathias Uhlén , Juris Viksna , Fredrik Ponten , Konstantin Skryabin , Ewan Birney , Ake Borg , Anne-Lise Børresen-Dale , Carlos Caldas , John A. Foekens , Martin Sancha , Jorge S. Reis-Filho , Andrea L. Richardson , Christos Sotiriou , Hendrik G. Stunnenberg , Laura Van'T Veer , Daniel Birnbaum , Hélène Blanché , Pascal Boucher , Sandrine Boyault , Jocelyne D Masson-Jacquemier , Iris Pauporté , Xavier Pivot , Anne Vincent-Salomon , Eric Tabone , Charles Theillet , Isabelle Treilleux , Paulette Bioulac-Sage , Thomas Decaens , Dominique Franco , Marta Gut , Didier Samuel , Jessica Zucman-Rossi , Roland Eils , Benedikt Brors , Jan O. Korbel , Andrey Korshunov , Pablo Landgraf , Hans Lehrach , Stefan Pfister , Bernhard Radlwimmer , Guido Reifenberger , Michael D. Taylor , Christof von Kalle , Partha P. Majumder , Paolo Pederzoli , Rita T. Lawlor , Massimo Delledonne , Alberto Bardelli , Thomas Gress , David Klimstra , Giuseppe Zamboni , Yusuke Nakamura , Satoru Miyano , Akihiro Fujimoto , Elias Campo , Silvia de Sanjosé , Emili Montserrat , Marcos González-Díaz , Pedro Jares , Heinz Himmelbaue , Silvia Bea , Samuel Aparicio , Douglas F. Easton , Eric S. Lander , Wylie Burke , Francis S. Collins , Carolyn C. Compton , Anthony R. Green , Stanley R. Hamilton , Olli P. Kallioniemi , Timothy J. Ley , Edison T. Liu , Brandon J. Wainwright

1 Foie, métabolismes et cancer

The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumors from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of over 25,000 cancer genomes at the genomic, epigenomic, and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically-relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.

Domaines: Hépatologie et Gastroentérologie

Thomas J. Hudson, Warwick Anderson, Axel Artez, Anna D. Barker, Cindy Bell, et al.. International network of cancer genome projects.. Nature, 2010, 464 (7291), pp.993-8. ⟨10.1038/nature08987⟩. ⟨hal-00868358⟩