The Chemical Composition and Antibacterial Activities of the Essential Oils from Three Aframomum Species from Cameroon, and Their Potential as Sources of (E)-(R)-Nerolidol

Sylvie Kwanga Nguikwie 1 Maximilienne A. Nyegue 2 Florentine Ndoye-Foe Belinga 2 Rosalie A. Ngono Ngane 3 Bernard Romestand 4 Achraf Kouzayha 4 Hervé Casabianca 5 Paul H. Amvam Zollo 2 Chantal Menut 4
1 Equipe Réponse Immunitaire des Macroorganismes et Environnement (RIME): UMR 5119
Ecosym - Ecologie des systèmes marins côtiers, Laboratoire de Phytobiochimie et d'Etude des Plantes Médicinales, Laboratoire de Biochimie
4 Equipe "Glyco et nanovecteurs pour le ciblage thérapeutique"
IBMM - Institut des Biomolécules Max Mousseron [Pôle Chimie Balard]
5 Produits naturels
ISA - Institut des Sciences Analytiques
Abstract : Essential oils obtained by hydrodistillation of seeds, pericarps, leaves and rhizomes of Aframomum dalzielii, A. letestuianum and A. pruinosum grown in Cameroon were analyzed by GC-FID and GC-MS. The seed oils of the three species were characterized by a high content of (E)-(R)-nerolidol (>88.0 %), which was fully characterized by NMR spectroscopy and chiral GC analysis. The main constituents of the pericarp and rhizome oils were monoterpene hydrocarbons, mainly beta-pinene (0.8%-22.9%) and sabinene (29.0%-42.3%), along with 1,8-cineole (4.5%-23.7%); leaf oils were characterized by sesquiterpenes, namely (E)-beta-caryophyllene (18.4%-82.4%) and caryophyllene oxide (4.5%-23.7%). The antibacterial activities of these essential oils and of nine pure compounds (sabirtene, beta-pinene, 1,8-cineole, linalool, racemic (E)-nerolidol, (E)-(R)-nerolidol, (E)-beta-caryophyllene, a-humulene and caryophyllene oxide) were assessed against Micrococcus luteus and Escherichia coli. The strongest activities were observed against E. coli. The seed essential oils and their major component, (E)-(R)-nerolidol, exhibited the lowest MIC values (0.19-0.39 mu L/mL), justifying their traditional use and their potential application as natural food preservatives.
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Submitted on : Wednesday, September 11, 2013 - 10:20:13 AM
Last modification on : Thursday, May 3, 2018 - 11:56:01 AM

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  • HAL Id : hal-00860789, version 1

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Sylvie Kwanga Nguikwie, Maximilienne A. Nyegue, Florentine Ndoye-Foe Belinga, Rosalie A. Ngono Ngane, Bernard Romestand, et al.. The Chemical Composition and Antibacterial Activities of the Essential Oils from Three Aframomum Species from Cameroon, and Their Potential as Sources of (E)-(R)-Nerolidol. Natural Product Communications, 2013, 8 (6), pp.829-834. 〈hal-00860789〉

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