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Conference papers
Bayesian Joint Detection-Estimation of cerebral vasoreactivity from ASL fMRI data
Abstract : Although the study of cerebral vasoreactivity using fMRI is mainly conducted through the BOLD fMRI modality, owing to its relatively high signal-to-noise ratio (SNR), ASL fMRI provides a more interpretable measure of cerebral vasoreactivity than BOLD fMRI. Still, ASL suffers from a low SNR and is hampered by a large amount of physiological noise. The current contribution aims at improving the re- covery of the vasoreactive component from the ASL signal. To this end, a Bayesian hierarchical model is proposed, enabling the recovery of per- fusion levels as well as fitting their dynamics. On a single-subject ASL real data set involving perfusion changes induced by hypercapnia, the approach is compared with a classical GLM-based analysis. A better goodness-of-fit is achieved, especially in the transitions between baseline and hypercapnia periods. Also, perfusion levels are recovered with higher sensitivity and show a better contrast between gray- and white matter.
Cited literature [11 references]
https://hal.inria.fr/hal-00854437
Contributor : Thomas Vincent <>
Submitted on : Tuesday, August 27, 2013 - 11:14:03 AM
Last modification on : Tuesday, November 24, 2020 - 4:38:03 PM
Long-term archiving on: : Thursday, April 6, 2017 - 9:18:14 AM
Contributor : Thomas Vincent <>
Submitted on : Tuesday, August 27, 2013 - 11:14:03 AM
Last modification on : Tuesday, November 24, 2020 - 4:38:03 PM
Long-term archiving on: : Thursday, April 6, 2017 - 9:18:14 AM
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