On inverse analysis and robustness evaluation for biological structure behaviour in FE simulation. Application to the liver

Cécile Conte (1) , Catherine Masson (1) , Pierre-Jean Arnoux (1)

1 LBA UMR T24 - Laboratoire de Biomécanique Appliquée

To prevent abdominal organs traumas, the definition of efficient safety devices should be based on a detailed knowledge of injury mechanisms and related injury criteria. In this sense, FE simulation coupled to experiment could be a valuable tool to provide a better understanding of internal organs behaviour under crash conditions. This work proposes a methodology based on inverse analysis which combines exploration process optimisation and robustness study to obtain mechanical behaviour of the complex structure of the liver through FE simulation. The liver characterisation was build on Mooney Rivlin hyperelastic behaviour law considering whole liver structure under uniform quasi-static compression. With the global method used, the model fits experimental data. The variability induced by modelling parameters is quantified within a reasonable time. Liver compression, FE simulation, inverse analysis, robustness analysis.

Mots clés: METHODE DES ELEMENTS FINIS; COMPRESSION; MODELE NUMERIQUE; VISCERES; ESSAI

Domaines: Ingénierie biomédicale

Cécile Conte, Catherine Masson, Pierre-Jean Arnoux. On inverse analysis and robustness evaluation for biological structure behaviour in FE simulation. Application to the liver. Computer Methods in Biomechanics and Biomedical Engineering, 2012, 15 (9), pp993-999. ⟨10.1080/10255842.2011.569884⟩. ⟨hal-00851267⟩