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Material density mapping on deformable 3D models of human organs

Abstract : Organ motion, especially respiratory motion, is a technical challenge to radiation therapy planning and dosimetry. This motion induces displacements and deformation of the organ tissues within the irradiated region which need to be taken into account when simulating dose distribution during treatment. Finite element modeling (FEM) can provide a great insight into the mechanical behavior of the organs, since they are based on the biomechanical material properties, complex geometry of organs, and anatomical boundary conditions. In this paper we present an original approach that offers the possibility to combine image-based biomechanical models with particle transport simulations. We propose a new method to map material density information issued from CT images to deformable tetrahedral meshes. Based on the principle of mass conservation our method can correlate density variation of organ tissues with geometrical deformations during the different phases of the respiratory cycle. The first results are particularly encouraging, as local error quantification of density mapping on organ geometry and density variation with organ motion are performed to evaluate and validate our approach.
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https://hal.archives-ouvertes.fr/hal-00838834
Contributor : Béatrice Rayet <>
Submitted on : Wednesday, June 26, 2013 - 4:25:27 PM
Last modification on : Tuesday, November 19, 2019 - 2:45:26 AM

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  • HAL Id : hal-00838834, version 1

Citation

P. Manescu, Joseph Azencot, M. Beuve, H. Ladjal, J. Saadé, et al.. Material density mapping on deformable 3D models of human organs. ICBBE 2012 : International Conference on Biomechanics and Biomedical Engineering, Jun 2012, Copenhagen, Denmark. pp.131-140. ⟨hal-00838834⟩

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