Novel Mechanisms for Augmenting Diabetic Wound Healing

Abstract : Impaired diabetic wound healing is multi-factorial and incompletely understood. Reactive oxygen species (ROS) and p53, a master gene regulator, are upregulated in diabetic wounds. We have demonstrated improved diabetic wound healing through a novel topical p53 silencing system. We hypothesized that topical silencing of p53 improves diabetic wound healing through a decrease in ROS.
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Journal of Surgical Research, Elsevier, 2010, 158 (2), pp.322. <10.1016/j.jss.2009.11.416>
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https://hal-mines-paristech.archives-ouvertes.fr/hal-00836604
Contributeur : Sylvie Lavigne <>
Soumis le : vendredi 21 juin 2013 - 11:07:46
Dernière modification le : mardi 12 septembre 2017 - 11:41:38

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D. Knobel, J.L. Crawford, P. D. Nguyen, J. Tutela, V.D. Thanik, et al.. Novel Mechanisms for Augmenting Diabetic Wound Healing. Journal of Surgical Research, Elsevier, 2010, 158 (2), pp.322. <10.1016/j.jss.2009.11.416>. <hal-00836604>

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