Mesenchymal Stem Cell Classification During Differentiation Based on Shape Information
Résumé
no abstractRegenerative therapy using the patient's stem cells is a promising approach for the regeneration of the locomotory system, e.g. 1 bone, cartilage and the intervertebral disc . "Stemness" (ability to differentiate into various tissue types) of in vitro cultures is difficult to predict due to the heterogeneous nature of cell populations. Here, we investigate whether commitment of stem cells can be tracked using descriptors of shape extracted from 2D time- lapse phase-contrast microscopy data.