Skip to Main content Skip to Navigation
Journal articles

Modeling protein-mediated morphology in biomembranes

Abstract : The equilibrium theory for lipid membranes is used to describe the structure of nuclear pores and the membrane shapes accompanying endocytosis. The commonly used variant of the theory contains a fixed parameter called the spontaneous curvature which accounts for asymmetry in the bending response of the membrane. This is replaced here by a variable distribution of spontaneous curvature representing the influence of attached proteins. The required adjustments to the standard theory are described and the resulting model is applied to the study of membrane morphology at the cites of protein-assisted nuclear pore formation and endocytosis.
Complete list of metadata

Cited literature [12 references]  Display  Hide  Download
Contributor : Francesco Dell'Isola Connect in order to contact the contributor
Submitted on : Wednesday, January 9, 2013 - 11:31:38 AM
Last modification on : Wednesday, August 7, 2019 - 12:19:22 PM
Long-term archiving on: : Saturday, April 1, 2017 - 2:36:11 AM


Files produced by the author(s)


  • HAL Id : hal-00771715, version 1


Ashutosh Agrawal, David Steigmann. Modeling protein-mediated morphology in biomembranes. Biomechanics and Modeling in Mechanobiology, Springer Verlag, 2009, 8 (5), pp.371-379. ⟨hal-00771715⟩



Record views


Files downloads