Synthesis and self-assembly of "tree-like" amphiphilic glycopolypeptides

Abstract : Novel synthetic tree-like oligosaccharides-grafted-polypeptides were prepared by using Huisgen 1,3-dipolar cycloaddition between poly(gamma-benzyl-L-glutamate)-block-poly(propargylglycine) and two different oligosaccharides, dextran or hyaluronan. By direct solubilisation in water, these tree- ike glycopeptides spontaneously form very small assemblies with sizes below 50 nm and low polydispersity.
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https://hal.archives-ouvertes.fr/hal-00757834
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Submitted on : Tuesday, November 27, 2012 - 4:28:12 PM
Last modification on : Thursday, January 11, 2018 - 6:28:10 AM

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Colin Bonduelle, Jin Huang, Emmanuel Ibarboure, Andreas Heise, Sébastien Lecommandoux. Synthesis and self-assembly of "tree-like" amphiphilic glycopolypeptides. Chemical Communications, Royal Society of Chemistry, 2012, 48 (67), pp.8353-8355. ⟨10.1039/c2cc32970k⟩. ⟨hal-00757834⟩

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