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Article Dans Une Revue Applied Mathematics Letters Année : 2012

Mathematical modelling of erythropoiesis in vivo with multiple erythroblastic islands.

Résumé

Erythropoiesis is a process of red blood cell production, which occurs mainly in the bone marrow. It is organized as a large number of small units called erythroblastic islands, each of them containing several dozens of cells. We show that the system of islands is unstable and that stable and constant production of erythrocytes cannot be achieved without a local control mechanism possibly provided by macrophages.

Dates et versions

hal-00753093 , version 1 (17-11-2012)

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Nikolai Bessonov, Nathalie Eymard, Polina Kurbatova, Vitaly Volpert. Mathematical modelling of erythropoiesis in vivo with multiple erythroblastic islands.. Applied Mathematics Letters, 2012, 25 (9), pp.1217-1221. ⟨10.1016/j.aml.2012.02.053⟩. ⟨hal-00753093⟩
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