Exploring the Physical Limits of Saturation Contrast in Magnetic Resonance Imaging

Abstract : Magnetic Resonance Imaging has become nowadays an indispensable tool with applications ranging from medicine to material science. However, so far the physical limits of the maximum achievable experimental contrast were unknown. We introduce an approach based on principles of optimal control theory to explore these physical limits, providing a benchmark for numerically optimized robust pulse sequences which can take into account experimental imperfections. This approach is demonstrated experimentally using a model system of two spatially separated liquids corresponding to blood in its oxygenated and deoxygenated forms.
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https://hal.archives-ouvertes.fr/hal-00750055
Contributor : Dominique Sugny <>
Submitted on : Thursday, November 8, 2012 - 11:19:09 PM
Last modification on : Friday, June 8, 2018 - 2:50:14 PM

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M. Lapert, Y. Zhang, M. A. Janich, S. J. Glaser, Dominique Sugny. Exploring the Physical Limits of Saturation Contrast in Magnetic Resonance Imaging. Scientific Reports, Nature Publishing Group, 2012, 2, pp.589. ⟨10.1038/srep00589⟩. ⟨hal-00750055⟩

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