Galvestine-1, a novel chemical probe for the study of the glycerolipid homeostasis system in plant cells.

Abstract : Plant cells are characterized by the presence of chloroplasts, membrane lipids of which contain up to ∼80% mono- and digalactosyldiacylglycerol (MGDG and DGDG). The synthesis of MGDG in the chloroplast envelope is essential for the biogenesis and function of photosynthetic membranes, is coordinated with lipid metabolism in other cell compartments and is regulated in response to environmental factors. Phenotypic analyses of Arabidopsis using the recently developed specific inhibitor called galvestine-1 complete previous analyses performed using various approaches, from enzymology, cell biology to genetics. This review details how this probe could be beneficial to study the lipid homeostasis system at the whole cell level and highlights connections between MGDG synthesis and Arabidopsis flower development.
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-00720135
Contributor : Jacqueline Martin-Laffon <>
Submitted on : Monday, July 23, 2012 - 4:56:21 PM
Last modification on : Tuesday, October 15, 2019 - 11:20:02 AM

Identifiers

Citation

Laurence Boudière, Cyrille Y Botté, Nadia Saidani, Mathieu Lajoie, Jessica Marion, et al.. Galvestine-1, a novel chemical probe for the study of the glycerolipid homeostasis system in plant cells.. Molecular BioSystems, Royal Society of Chemistry, 2012, 8 (8), pp.2023-35. ⟨10.1039/c2mb25067e⟩. ⟨hal-00720135⟩

Share

Metrics

Record views

6890